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A modified HSP70 inhibitor shows broad activity as an anticancer agent.
Mol Cancer Res. 2013 Mar;11(3):219-29. doi: 10.1158/1541-7786.MCR-12-0547-T. Epub 2013 Jan 9.
Mol Cancer Res. 2013.
PMID: 23303345
Free PMC article.
Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition.
Budina-Kolomets A, Balaburski GM, Bondar A, Beeharry N, Yen T, Murphy ME.
Budina-Kolomets A, et al. Among authors: balaburski gm.
Cancer Biol Ther. 2014 Feb;15(2):194-9. doi: 10.4161/cbt.26720. Epub 2013 Nov 1.
Cancer Biol Ther. 2014.
PMID: 24100579
Free PMC article.
Item in Clipboard
p53 and ARF: unexpected players in autophagy.
Balaburski GM, Hontz RD, Murphy ME.
Balaburski GM, et al.
Trends Cell Biol. 2010 Jun;20(6):363-9. doi: 10.1016/j.tcb.2010.02.007. Epub 2010 Mar 19.
Trends Cell Biol. 2010.
PMID: 20303758
Free PMC article.
Review.
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Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C.
Lum MA, Balaburski GM, Murphy ME, Black AR, Black JD.
Lum MA, et al. Among authors: balaburski gm.
J Biol Chem. 2013 Sep 20;288(38):27112-27127. doi: 10.1074/jbc.M112.437095. Epub 2013 Jul 30.
J Biol Chem. 2013.
PMID: 23900841
Free PMC article.
Item in Clipboard
Autophagy in tumor suppression and cancer therapy.
Kung CP, Budina A, Balaburski G, Bergenstock MK, Murphy M.
Kung CP, et al.
Crit Rev Eukaryot Gene Expr. 2011;21(1):71-100. doi: 10.1615/critreveukargeneexpr.v21.i1.50.
Crit Rev Eukaryot Gene Expr. 2011.
PMID: 21967333
Free PMC article.
Review.
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Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence.
Whibley C, Odell AF, Nedelko T, Balaburski G, Murphy M, Liu Z, Stevens L, Walker JH, Routledge M, Hollstein M.
Whibley C, et al.
J Biol Chem. 2010 Apr 9;285(15):11326-35. doi: 10.1074/jbc.M109.064444. Epub 2010 Jan 29.
J Biol Chem. 2010.
PMID: 20118236
Free PMC article.
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Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: a unifying concept in anti-hormone resistance.
Balaburski GM, Dardes RC, Johnson M, Haddad B, Zhu F, Ross EA, Sengupta S, Klein-Szanto A, Liu H, Lee ES, Kim H, Jordan VC.
Balaburski GM, et al.
Int J Oncol. 2010 Aug;37(2):387-98. doi: 10.3892/ijo_00000687.
Int J Oncol. 2010.
PMID: 20596666
Free PMC article.
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