Pommier Y - Search Results

1

Development and validation of an immunoassay for quantification of topoisomerase I in solid tumor tissues.

Pfister TD, Hollingshead M, Kinders RJ, Zhang Y, Evrard YA, Ji J, Khin SA, Borgel S, Stotler H, Carter J, Divelbiss R, Kummar S, Pommier Y, Parchment RE, Tomaszewski JE, Doroshow JH. Pfister TD, et al. Among authors: pommier y. PLoS One. 2012;7(12):e50494. doi: 10.1371/journal.pone.0050494. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23284638 Free PMC article.

2

Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line.

Urasaki Y, Laco GS, Pourquier P, Takebayashi Y, Kohlhagen G, Gioffre C, Zhang H, Chatterjee D, Pantazis P, Pommier Y. Urasaki Y, et al. Among authors: pommier y. Cancer Res. 2001 Mar 1;61(5):1964-9. Cancer Res. 2001. PMID: 11280753

3

Synthesis of new dihydroindeno[1,2-c]isoquinoline and indenoisoquinolinium chloride topoisomerase I inhibitors having high in vivo anticancer activity in the hollow fiber animal model.

Jayaraman M, Fox BM, Hollingshead M, Kohlhagen G, Pommier Y, Cushman M. Jayaraman M, et al. Among authors: pommier y. J Med Chem. 2002 Jan 3;45(1):242-9. doi: 10.1021/jm000498f. J Med Chem. 2002. PMID: 11754595

4

Apoptosis induced by topoisomerase inhibitors.

Sordet O, Khan QA, Kohn KW, Pommier Y. Sordet O, et al. Among authors: pommier y. Curr Med Chem Anticancer Agents. 2003 Jul;3(4):271-90. doi: 10.2174/1568011033482378. Curr Med Chem Anticancer Agents. 2003. PMID: 12769773 Review.

5

A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.

Liao ZY, Sordet O, Zhang HL, Kohlhagen G, Antony S, Gmeiner WH, Pommier Y. Liao ZY, et al. Among authors: pommier y. Cancer Res. 2005 Jun 1;65(11):4844-51. doi: 10.1158/0008-5472.CAN-04-1302. Cancer Res. 2005. PMID: 15930305

6

Evaluation of indenoisoquinoline topoisomerase I inhibitors using a hollow fiber assay.

Morrell A, Jayaraman M, Nagarajan M, Fox BM, Meckley MR, Ioanoviciu A, Pommier Y, Antony S, Hollingshead M, Cushman M. Morrell A, et al. Among authors: pommier y. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4395-9. doi: 10.1016/j.bmcl.2006.05.048. Epub 2006 Jun 5. Bioorg Med Chem Lett. 2006. PMID: 16750365

7

Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.

Antony S, Agama KK, Miao ZH, Hollingshead M, Holbeck SL, Wright MH, Varticovski L, Nagarajan M, Morrell A, Cushman M, Pommier Y. Antony S, et al. Among authors: pommier y. Mol Pharmacol. 2006 Sep;70(3):1109-20. doi: 10.1124/mol.106.024372. Epub 2006 Jun 23. Mol Pharmacol. 2006. PMID: 16798938

8

Synthesis and biological evaluation of bisindenoisoquinolines as topoisomerase I inhibitors.

Nagarajan M, Morrell A, Antony S, Kohlhagen G, Agama K, Pommier Y, Ragazzon PA, Garbett NC, Chaires JB, Hollingshead M, Cushman M. Nagarajan M, et al. Among authors: pommier y. J Med Chem. 2006 Aug 24;49(17):5129-40. doi: 10.1021/jm060046o. J Med Chem. 2006. PMID: 16913702

9

Topoisomerase I inhibitors: camptothecins and beyond.

Pommier Y. Pommier Y. Nat Rev Cancer. 2006 Oct;6(10):789-802. doi: 10.1038/nrc1977. Nat Rev Cancer. 2006. PMID: 16990856 Review.

10

Synthesis and evaluation of indenoisoquinoline topoisomerase I inhibitors substituted with nitrogen heterocycles.

Nagarajan M, Morrell A, Ioanoviciu A, Antony S, Kohlhagen G, Agama K, Hollingshead M, Pommier Y, Cushman M. Nagarajan M, et al. Among authors: pommier y. J Med Chem. 2006 Oct 19;49(21):6283-9. doi: 10.1021/jm060564z. J Med Chem. 2006. PMID: 17034134 Free PMC article.

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