Sanderson T - Search Results

1

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

Albright CF, Dockens RC, Meredith JE Jr, Olson RE, Slemmon R, Lentz KA, Wang JS, Denton RR, Pilcher G, Rhyne PW, Raybon JJ, Barten DM, Burton C, Toyn JH, Sankaranarayanan S, Polson C, Guss V, White R, Simutis F, Sanderson T, Gillman KW, Starrett JE Jr, Bronson J, Sverdlov O, Huang SP, Castaneda L, Feldman H, Coric V, Zaczek R, Macor JE, Houston J, Berman RM, Tong G. Albright CF, et al. Among authors: sanderson t. J Pharmacol Exp Ther. 2013 Mar;344(3):686-95. doi: 10.1124/jpet.112.199356. Epub 2012 Dec 28. J Pharmacol Exp Ther. 2013. PMID: 23275065

2

Nonclinical Safety Assessment of the γ-Secretase Inhibitor Avagacestat.

Simutis FJ, Sanderson TP, Pilcher GD, Graziano MJ. Simutis FJ, et al. Toxicol Sci. 2018 Jun 1;163(2):525-542. doi: 10.1093/toxsci/kfy048. Toxicol Sci. 2018. PMID: 29529279

3

Determination of relative Notch1 and gamma-secretase-related gene expression in puromycin-treated microdissected rat kidneys.

Simic D, Simutis F, Euler C, Thurby C, Peden WM, Bunch RT, Pilcher G, Sanderson T, Van Vleet T. Simic D, et al. Among authors: sanderson t. Gene Expr. 2013;16(1):39-47. doi: 10.3727/105221613x13806435102312. Gene Expr. 2013. PMID: 24397211 Free PMC article.

4

Investigations on the Relationship Between Ovarian, Endocrine, and Renal Findings in Nonclinical Safety Studies of the γ-Secretase Inhibitor Avagacestat.

Simutis FJ, Sanderson TP, Pilcher GD, Graziano MJ. Simutis FJ, et al. Toxicol Sci. 2019 Sep 1;171(1):98-116. doi: 10.1093/toxsci/kfz129. Toxicol Sci. 2019. PMID: 31165171

5

D-α-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage.

Baumgart BR, Van Vleet TR, Simic D, Salcedo TW, Lentz K, Donegan M, Davies MH, Bunch RT, Sanderson TP, Lange RW. Baumgart BR, et al. Among authors: sanderson tp. J Appl Toxicol. 2015 Jul;35(7):791-8. doi: 10.1002/jat.3072. Epub 2014 Oct 28. J Appl Toxicol. 2015. PMID: 25348750

6

From the Cover: Investigative Nonclinical Cardiovascular Safety and Toxicology Studies with BMS-986094, an NS5b RNA-Dependent RNA Polymerase Inhibitor.

Gill M, Horn K, Hennan J, White R, Bounous D, Clark S, Megill JR, Janovitz E, Davies M, Sanderson T, Graziano M. Gill M, et al. Among authors: sanderson t. Toxicol Sci. 2017 Feb;155(2):348-362. doi: 10.1093/toxsci/kfw211. Epub 2016 Nov 17. Toxicol Sci. 2017. PMID: 27864544

7

MicroRNA as biomarkers of mitochondrial toxicity.

Baumgart BR, Gray KL, Woicke J, Bunch RT, Sanderson TP, Van Vleet TR. Baumgart BR, et al. Among authors: sanderson tp. Toxicol Appl Pharmacol. 2016 Dec 1;312:26-33. doi: 10.1016/j.taap.2015.10.007. Epub 2015 Oct 23. Toxicol Appl Pharmacol. 2016. PMID: 26476301

8

In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension.

Baumgart B, Guha M, Hennan J, Li J, Woicke J, Simic D, Graziano M, Wallis N, Sanderson T, Bunch RT. Baumgart B, et al. Among authors: sanderson t. Cancer Chemother Pharmacol. 2017 Apr;79(4):711-723. doi: 10.1007/s00280-017-3264-2. Epub 2017 Mar 10. Cancer Chemother Pharmacol. 2017. PMID: 28283735

9

Toxicity of Pexacerfont, a Corticotropin-Releasing Factor Type 1 Receptor Antagonist, in Rats and Dogs.

White MR, Graziano MJ, Sanderson TP. White MR, et al. Int J Toxicol. 2019 Mar/Apr;38(2):110-120. doi: 10.1177/1091581819827501. Epub 2019 Feb 13. Int J Toxicol. 2019. PMID: 30760067

10

Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.

Mausumee G, Frank S, Shawn C, Dara H, Zhao Y, Soleil PM, Sanderson TP, Michael G, Marc D. Mausumee G, et al. Int J Toxicol. 2014 May;33(3):204-218. doi: 10.1177/1091581814529309. Int J Toxicol. 2014. PMID: 24846376

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