Bhagwat AS - Search Results

1

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent.

Chan K, Sterling JF, Roberts SA, Bhagwat AS, Resnick MA, Gordenin DA. Chan K, et al. Among authors: bhagwat as. PLoS Genet. 2012;8(12):e1003149. doi: 10.1371/journal.pgen.1003149. Epub 2012 Dec 13. PLoS Genet. 2012. PMID: 23271983 Free PMC article.

2

Transcription-associated mutagenesis.

Jinks-Robertson S, Bhagwat AS. Jinks-Robertson S, et al. Among authors: bhagwat as. Annu Rev Genet. 2014;48:341-59. doi: 10.1146/annurev-genet-120213-092015. Epub 2014 Sep 10. Annu Rev Genet. 2014. PMID: 25251854 Free PMC article. Review.

3

Unscheduled DNA synthesis leads to elevated uracil residues at highly transcribed genomic loci in Saccharomyces cerevisiae.

Owiti N, Wei S, Bhagwat AS, Kim N. Owiti N, et al. Among authors: bhagwat as. PLoS Genet. 2018 Jul 17;14(7):e1007516. doi: 10.1371/journal.pgen.1007516. eCollection 2018 Jul. PLoS Genet. 2018. PMID: 30016327 Free PMC article.

4

Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases.

Siriwardena SU, Chen K, Bhagwat AS. Siriwardena SU, et al. Among authors: bhagwat as. Chem Rev. 2016 Oct 26;116(20):12688-12710. doi: 10.1021/acs.chemrev.6b00296. Epub 2016 Sep 1. Chem Rev. 2016. PMID: 27585283 Free PMC article. Review.

5

Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli.

Bhagwat AS, Hao W, Townes JP, Lee H, Tang H, Foster PL. Bhagwat AS, et al. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2176-81. doi: 10.1073/pnas.1522325113. Epub 2016 Feb 2. Proc Natl Acad Sci U S A. 2016. PMID: 26839411 Free PMC article.

6

A novel class of chemicals that react with abasic sites in DNA and specifically kill B cell cancers.

Wei S, Perera MLW, Sakhtemani R, Bhagwat AS. Wei S, et al. Among authors: bhagwat as. PLoS One. 2017 Sep 19;12(9):e0185010. doi: 10.1371/journal.pone.0185010. eCollection 2017. PLoS One. 2017. PMID: 28926604 Free PMC article.

7

Genome-wide mapping of regions preferentially targeted by the human DNA-cytosine deaminase APOBEC3A using uracil-DNA pulldown and sequencing.

Sakhtemani R, Senevirathne V, Stewart J, Perera MLW, Pique-Regi R, Lawrence MS, Bhagwat AS. Sakhtemani R, et al. Among authors: bhagwat as. J Biol Chem. 2019 Oct 11;294(41):15037-15051. doi: 10.1074/jbc.RA119.008053. Epub 2019 Aug 19. J Biol Chem. 2019. PMID: 31431505 Free PMC article.

8

Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops.

Sakhtemani R, Perera MLW, Hübschmann D, Siebert R, Lawrence MS, Bhagwat AS. Sakhtemani R, et al. Among authors: bhagwat as. Nucleic Acids Res. 2022 May 20;50(9):5145-5157. doi: 10.1093/nar/gkac296. Nucleic Acids Res. 2022. PMID: 35524550 Free PMC article.

9

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations.

Sohail A, Klapacz J, Samaranayake M, Ullah A, Bhagwat AS. Sohail A, et al. Among authors: bhagwat as. Nucleic Acids Res. 2003 Jun 15;31(12):2990-4. doi: 10.1093/nar/gkg464. Nucleic Acids Res. 2003. PMID: 12799424 Free PMC article.

10

A versatile new tool to quantify abasic sites in DNA and inhibit base excision repair.

Wei S, Shalhout S, Ahn YH, Bhagwat AS. Wei S, et al. Among authors: bhagwat as. DNA Repair (Amst). 2015 Mar;27:9-18. doi: 10.1016/j.dnarep.2014.12.006. Epub 2015 Jan 6. DNA Repair (Amst). 2015. PMID: 25616257 Free PMC article.

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