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Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations.
Houlden H, Baker M, McGowan E, Lewis P, Hutton M, Crook R, Wood NW, Kumar-Singh S, Geddes J, Swash M, Scaravilli F, Holton JL, Lashley T, Tomita T, Hashimoto T, Verkkoniemi A, Kalimo H, Somer M, Paetau A, Martin JJ, Van Broeckhoven C, Golde T, Hardy J, Haltia M, Revesz T. Houlden H, et al. Among authors: holton jl. Ann Neurol. 2000 Nov;48(5):806-8. Ann Neurol. 2000. PMID: 11079548
Systemic amyloid deposits in familial British dementia.
Ghiso JA, Holton J, Miravalle L, Calero M, Lashley T, Vidal R, Houlden H, Wood N, Neubert TA, Rostagno A, Plant G, Revesz T, Frangione B. Ghiso JA, et al. Among authors: holton j. J Biol Chem. 2001 Nov 23;276(47):43909-14. doi: 10.1074/jbc.M105956200. Epub 2001 Sep 13. J Biol Chem. 2001. PMID: 11557758 Free article.
Chromosome 13 dementia syndromes as models of neurodegeneration.
Ghiso J, Révész T, Holton J, Rostagno A, Lashley T, Houlden H, Gibb G, Anderton B, Bek T, Bojsen-Møller M, Wood N, Vidal R, Braendgaard H, Plant G, Frangione B. Ghiso J, et al. Among authors: holton j. Amyloid. 2001 Dec;8(4):277-84. doi: 10.3109/13506120108993826. Amyloid. 2001. PMID: 11791622 Review.
721 results