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Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7.
Vergani A, Tezza S, D'Addio F, Fotino C, Liu K, Niewczas M, Bassi R, Molano RD, Kleffel S, Petrelli A, Soleti A, Ammirati E, Frigerio M, Visner G, Grassi F, Ferrero ME, Corradi D, Abdi R, Ricordi C, Sayegh MH, Pileggi A, Fiorina P. Vergani A, et al. Among authors: liu k. Circulation. 2013 Jan 29;127(4):463-75. doi: 10.1161/CIRCULATIONAHA.112.123653. Epub 2012 Dec 18. Circulation. 2013. PMID: 23250993 Free PMC article.
P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.
D'Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, Bassi R, Tezza S, Dellepiane S, El Essawy B, Iascone M, Iacovoni A, Borgese L, Liu K, Visner G, Dhe-Paganon S, Corradi D, Abdi R, Starling RC, Folli F, Zuccotti GV, Sayegh MH, Heeger PS, Chandraker A, Grigioni F, Fiorina P. D'Addio F, et al. Among authors: liu k. J Clin Invest. 2018 Aug 1;128(8):3490-3503. doi: 10.1172/JCI94524. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 30010623 Free PMC article.
Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms.
Magee CN, Murakami N, Borges TJ, Shimizu T, Safa K, Ohori S, Cai S, Uffing A, Azzi J, Elyaman W, Charbonnier LM, Liu K, Toprak D, Visner G, Chatila TA, Siebel CW, Najafian N, Riella LV. Magee CN, et al. Among authors: liu k. Circulation. 2019 Sep 9;140(10):846-863. doi: 10.1161/CIRCULATIONAHA.119.040563. Epub 2019 Jul 3. Circulation. 2019. PMID: 31266349 Free PMC article.
A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice.
Vergani A, D'Addio F, Jurewicz M, Petrelli A, Watanabe T, Liu K, Law K, Schuetz C, Carvello M, Orsenigo E, Deng S, Rodig SJ, Ansari JM, Staudacher C, Abdi R, Williams J, Markmann J, Atkinson M, Sayegh MH, Fiorina P. Vergani A, et al. Among authors: liu k. Diabetes. 2010 Sep;59(9):2253-64. doi: 10.2337/db09-1264. Diabetes. 2010. PMID: 20805386 Free PMC article.
miR-21 antagonism reprograms macrophage metabolism and abrogates chronic allograft vasculopathy.
Usuelli V, Ben Nasr M, D'Addio F, Liu K, Vergani A, El Essawy B, Yang J, Assi E, Uehara M, Rossi C, Solini A, Capobianco A, Rigamonti E, Potena L, Venturini M, Sabatino M, Bottarelli L, Ammirati E, Frigerio M, Castillo-Leon E, Maestroni A, Azzoni C, Loretelli C, Joe Seelam A, Tai AK, Pastore I, Becchi G, Corradi D, Visner GA, Zuccotti GV, Chau NB, Abdi R, Pezzolesi MG, Fiorina P. Usuelli V, et al. Among authors: liu k. Am J Transplant. 2021 Oct;21(10):3280-3295. doi: 10.1111/ajt.16581. Epub 2021 May 3. Am J Transplant. 2021. PMID: 33764625 Free PMC article.
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