Ewald F - Search Results

1

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells.

Grabinski N, Ewald F, Hofmann BT, Staufer K, Schumacher U, Nashan B, Jücker M. Grabinski N, et al. Among authors: ewald f. Mol Cancer. 2012 Nov 20;11:85. doi: 10.1186/1476-4598-11-85. Mol Cancer. 2012. PMID: 23167739 Free PMC article.

2

Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma.

Ewald F, Grabinski N, Grottke A, Windhorst S, Nörz D, Carstensen L, Staufer K, Hofmann BT, Diehl F, David K, Schumacher U, Nashan B, Jücker M. Ewald F, et al. Int J Cancer. 2013 Nov;133(9):2065-76. doi: 10.1002/ijc.28214. Epub 2013 May 29. Int J Cancer. 2013. PMID: 23588885

3

Ibrutinib (ImbruvicaTM) potently inhibits ErbB receptor phosphorylation and cell viability of ErbB2-positive breast cancer cells.

Grabinski N, Ewald F. Grabinski N, et al. Among authors: ewald f. Invest New Drugs. 2014 Dec;32(6):1096-104. doi: 10.1007/s10637-014-0141-2. Epub 2014 Aug 1. Invest New Drugs. 2014. PMID: 25081321

4

Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors.

Ewald F, Nörz D, Grottke A, Hofmann BT, Nashan B, Jücker M. Ewald F, et al. Invest New Drugs. 2014 Dec;32(6):1144-54. doi: 10.1007/s10637-014-0149-7. Epub 2014 Aug 26. Invest New Drugs. 2014. PMID: 25152244

5

ABO blood group IgM isoagglutinins interact with tumor-associated O-glycan structures in pancreatic cancer.

Hofmann BT, Stehr A, Dohrmann T, Güngör C, Herich L, Hiller J, Harder S, Ewald F, Gebauer F, Tachezy M, Precht C, Izbicki JR, Bockhorn M, Wagener C, Wolters-Eisfeld G. Hofmann BT, et al. Among authors: ewald f. Clin Cancer Res. 2014 Dec 1;20(23):6117-26. doi: 10.1158/1078-0432.CCR-14-0716. Epub 2014 Oct 15. Clin Cancer Res. 2014. PMID: 25320359

6

ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.

Kebenko M, Drenckhan A, Gros SJ, Jücker M, Grabinski N, Ewald F, Grottke A, Schultze A, Izbicki JR, Bokemeyer C, Wellbrock J, Fiedler W. Kebenko M, et al. Among authors: ewald f. Cell Signal. 2015 Feb;27(2):373-81. doi: 10.1016/j.cellsig.2014.11.022. Epub 2014 Nov 27. Cell Signal. 2015. PMID: 25435423

7

COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.

Hofmann BT, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak AS, Harder S, El Gammal AT, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki JR, Jücker M, Bockhorn M, Wolters-Eisfeld G. Hofmann BT, et al. Among authors: ewald f. Mol Cancer. 2015 May 29;14:109. doi: 10.1186/s12943-015-0386-1. Mol Cancer. 2015. PMID: 26021314 Free PMC article.

8

Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion.

Nörz D, Grottke A, Bach J, Herzberger C, Hofmann BT, Nashan B, Jücker M, Ewald F. Nörz D, et al. Among authors: ewald f. Cell Signal. 2015 Nov;27(11):2191-200. doi: 10.1016/j.cellsig.2015.07.016. Epub 2015 Jul 22. Cell Signal. 2015. PMID: 26210887

9

Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma.

Ewald F, Nörz D, Grottke A, Bach J, Herzberger C, Hofmann BT, Nashan B, Jücker M. Ewald F, et al. J Cancer. 2015 Sep 16;6(12):1195-205. doi: 10.7150/jca.12452. eCollection 2015. J Cancer. 2015. PMID: 26535060 Free PMC article.

10

Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death.

Saran S, Tran DD, Ewald F, Koch A, Hoffmann A, Koch M, Nashan B, Tamura T. Saran S, et al. Among authors: ewald f. Oncogene. 2016 Jul 21;35(29):3872-9. doi: 10.1038/onc.2015.433. Epub 2015 Nov 9. Oncogene. 2016. PMID: 26549021

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