Waltho JP - Search Results

1

Reflections on biocatalysis involving phosphorus.

Blackburn GM, Bowler MW, Jin Y, Waltho JP. Blackburn GM, et al. Among authors: waltho jp. Biochemistry (Mosc). 2012 Oct;77(10):1083-96. doi: 10.1134/S000629791210001X. Biochemistry (Mosc). 2012. PMID: 23157289 Free article. Review.

2

Complexes formed between calmodulin and the antagonists J-8 and TFP in solution.

Craven CJ, Whitehead B, Jones SK, Thulin E, Blackburn GM, Waltho JP. Craven CJ, et al. Among authors: waltho jp. Biochemistry. 1996 Aug 13;35(32):10287-99. doi: 10.1021/bi9605043. Biochemistry. 1996. PMID: 8756684

3

A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site.

Baxter NJ, Olguin LF, Golicnik M, Feng G, Hounslow AM, Bermel W, Blackburn GM, Hollfelder F, Waltho JP, Williams NH. Baxter NJ, et al. Among authors: waltho jp. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14732-7. doi: 10.1073/pnas.0604448103. Epub 2006 Sep 21. Proc Natl Acad Sci U S A. 2006. PMID: 16990434 Free PMC article.

4

Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

Baxter NJ, Blackburn GM, Marston JP, Hounslow AM, Cliff MJ, Bermel W, Williams NH, Hollfelder F, Wemmer DE, Waltho JP. Baxter NJ, et al. Among authors: waltho jp. J Am Chem Soc. 2008 Mar 26;130(12):3952-8. doi: 10.1021/ja078000n. Epub 2008 Mar 5. J Am Chem Soc. 2008. PMID: 18318536

5

MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.

Baxter NJ, Hounslow AM, Bowler MW, Williams NH, Blackburn GM, Waltho JP. Baxter NJ, et al. Among authors: waltho jp. J Am Chem Soc. 2009 Nov 18;131(45):16334-5. doi: 10.1021/ja905972m. J Am Chem Soc. 2009. PMID: 19852484

6

Structural tightening and interdomain communication in the catalytic cycle of phosphoglycerate kinase.

Marston JP, Cliff MJ, Reed MA, Blackburn GM, Hounslow AM, Craven CJ, Waltho JP. Marston JP, et al. Among authors: waltho jp. J Mol Biol. 2010 Feb 19;396(2):345-60. doi: 10.1016/j.jmb.2009.11.052. Epub 2009 Nov 26. J Mol Biol. 2010. PMID: 19944703

7

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.

Baxter NJ, Bowler MW, Alizadeh T, Cliff MJ, Hounslow AM, Wu B, Berkowitz DB, Williams NH, Blackburn GM, Waltho JP. Baxter NJ, et al. Among authors: waltho jp. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4555-60. doi: 10.1073/pnas.0910333106. Epub 2010 Feb 17. Proc Natl Acad Sci U S A. 2010. PMID: 20164409 Free PMC article.

8

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

Cliff MJ, Bowler MW, Varga A, Marston JP, Szabó J, Hounslow AM, Baxter NJ, Blackburn GM, Vas M, Waltho JP. Cliff MJ, et al. Among authors: waltho jp. J Am Chem Soc. 2010 May 12;132(18):6507-16. doi: 10.1021/ja100974t. J Am Chem Soc. 2010. PMID: 20397725

9

Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.

Xiaoxia L, Marston JP, Baxter NJ, Hounslow AM, Yufen Z, Blackburn GM, Cliff MJ, Waltho JP. Xiaoxia L, et al. Among authors: waltho jp. J Am Chem Soc. 2011 Mar 23;133(11):3989-94. doi: 10.1021/ja1090035. Epub 2011 Feb 24. J Am Chem Soc. 2011. PMID: 21348513

10

Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.

Griffin JL, Bowler MW, Baxter NJ, Leigh KN, Dannatt HR, Hounslow AM, Blackburn GM, Webster CE, Cliff MJ, Waltho JP. Griffin JL, et al. Among authors: waltho jp. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6910-5. doi: 10.1073/pnas.1116855109. Epub 2012 Apr 13. Proc Natl Acad Sci U S A. 2012. PMID: 22505741 Free PMC article.

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