DeGrado WF - Search Results

1

Detection of drug-induced conformational change of a transmembrane protein in lipid bilayers using site-directed spin labeling.

Thomaston JL, Nguyen PA, Brown EC, Upshur MA, Wang J, DeGrado WF, Howard KP. Thomaston JL, et al. Among authors: degrado wf. Protein Sci. 2013 Jan;22(1):65-73. doi: 10.1002/pro.2186. Epub 2012 Nov 19. Protein Sci. 2013. PMID: 23139077 Free PMC article.

2

Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1.

Patterson WR, Anderson DH, DeGrado WF, Cascio D, Eisenberg D. Patterson WR, et al. Among authors: degrado wf. Protein Sci. 1999 Jul;8(7):1410-22. doi: 10.1110/ps.8.7.1410. Protein Sci. 1999. PMID: 10422829 Free PMC article.

3

Proton and metal ion-dependent assembly of a model diiron protein.

Pasternak A, Kaplan J, Lear JD, Degrado WF. Pasternak A, et al. Among authors: degrado wf. Protein Sci. 2001 May;10(5):958-69. doi: 10.1110/ps.52101. Protein Sci. 2001. PMID: 11316876 Free PMC article.

4

Sequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein.

Howard KP, Lear JD, DeGrado WF. Howard KP, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8568-72. doi: 10.1073/pnas.132266099. Proc Natl Acad Sci U S A. 2002. PMID: 12084917 Free PMC article.

5

Computational design of a water-soluble analog of phospholamban.

Slovic AM, Summa CM, Lear JD, DeGrado WF. Slovic AM, et al. Among authors: degrado wf. Protein Sci. 2003 Feb;12(2):337-48. doi: 10.1110/ps.0226603. Protein Sci. 2003. PMID: 12538897 Free PMC article.

6

The hydration of amides in helices; a comprehensive picture from molecular dynamics, IR, and NMR.

Walsh ST, Cheng RP, Wright WW, Alonso DO, Daggett V, Vanderkooi JM, DeGrado WF. Walsh ST, et al. Among authors: degrado wf. Protein Sci. 2003 Mar;12(3):520-31. doi: 10.1110/ps.0223003. Protein Sci. 2003. PMID: 12592022 Free PMC article.

7

How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles.

DeGrado WF, Gratkowski H, Lear JD. DeGrado WF, et al. Protein Sci. 2003 Apr;12(4):647-65. doi: 10.1110/ps.0236503. Protein Sci. 2003. PMID: 12649422 Free PMC article. Review.

8

Determination of membrane protein stability via thermodynamic coupling of folding to thiol-disulfide interchange.

Cristian L, Lear JD, DeGrado WF. Cristian L, et al. Among authors: degrado wf. Protein Sci. 2003 Aug;12(8):1732-40. doi: 10.1110/ps.0378603. Protein Sci. 2003. PMID: 12876322 Free PMC article.

9

Use of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers.

Cristian L, Lear JD, DeGrado WF. Cristian L, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14772-7. doi: 10.1073/pnas.2536751100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657351 Free PMC article.

10

Sequence determinants of a transmembrane proton channel: an inverse relationship between stability and function.

Stouffer AL, Nanda V, Lear JD, DeGrado WF. Stouffer AL, et al. Among authors: degrado wf. J Mol Biol. 2005 Mar 18;347(1):169-79. doi: 10.1016/j.jmb.2005.01.023. Epub 2005 Jan 21. J Mol Biol. 2005. PMID: 15733926

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