Lähdesmäki H - Search Results

1

An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation.

Aijö T, Edelman SM, Lönnberg T, Larjo A, Kallionpää H, Tuomela S, Engström E, Lahesmaa R, Lähdesmäki H. Aijö T, et al. Among authors: lahdesmaki h. BMC Genomics. 2012 Oct 30;13:572. doi: 10.1186/1471-2164-13-572. BMC Genomics. 2012. PMID: 23110343 Free PMC article.

2

In silico microdissection of microarray data from heterogeneous cell populations.

Lähdesmäki H, Shmulevich L, Dunmire V, Yli-Harja O, Zhang W. Lähdesmäki H, et al. BMC Bioinformatics. 2005 Mar 14;6:54. doi: 10.1186/1471-2105-6-54. BMC Bioinformatics. 2005. PMID: 15766384 Free PMC article.

3

A joint finite mixture model for clustering genes from independent Gaussian and beta distributed data.

Dai X, Erkkilä T, Yli-Harja O, Lähdesmäki H. Dai X, et al. Among authors: lahdesmaki h. BMC Bioinformatics. 2009 May 29;10:165. doi: 10.1186/1471-2105-10-165. BMC Bioinformatics. 2009. PMID: 19480678 Free PMC article.

4

Learning gene regulatory networks from gene expression measurements using non-parametric molecular kinetics.

Aijö T, Lähdesmäki H. Aijö T, et al. Among authors: lahdesmaki h. Bioinformatics. 2009 Nov 15;25(22):2937-44. doi: 10.1093/bioinformatics/btp511. Epub 2009 Aug 25. Bioinformatics. 2009. PMID: 19706742

5

Systematic analysis of disease-related regulatory mutation classes reveals distinct effects on transcription factor binding.

Laurila K, Lähdesmäki H. Laurila K, et al. Among authors: lahdesmaki h. In Silico Biol. 2009;9(4):209-24. In Silico Biol. 2009. PMID: 20109151

6

Reconstruction and validation of RefRec: a global model for the yeast molecular interaction network.

Aho T, Almusa H, Matilainen J, Larjo A, Ruusuvuori P, Aho KL, Wilhelm T, Lähdesmäki H, Beyer A, Harju M, Chowdhury S, Leinonen K, Roos C, Yli-Harja O. Aho T, et al. Among authors: lahdesmaki h. PLoS One. 2010 May 14;5(5):e10662. doi: 10.1371/journal.pone.0010662. PLoS One. 2010. PMID: 20498836 Free PMC article.

7

Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming.

Elo LL, Järvenpää H, Tuomela S, Raghav S, Ahlfors H, Laurila K, Gupta B, Lund RJ, Tahvanainen J, Hawkins RD, Oresic M, Lähdesmäki H, Rasool O, Rao KV, Aittokallio T, Lahesmaa R. Elo LL, et al. Among authors: lahdesmaki h. Immunity. 2010 Jun 25;32(6):852-62. doi: 10.1016/j.immuni.2010.06.011. Immunity. 2010. PMID: 20620947 Free article.

8

Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer.

Urbanucci A, Sahu B, Seppälä J, Larjo A, Latonen LM, Waltering KK, Tammela TL, Vessella RL, Lähdesmäki H, Jänne OA, Visakorpi T. Urbanucci A, et al. Among authors: lahdesmaki h. Oncogene. 2012 Apr 26;31(17):2153-63. doi: 10.1038/onc.2011.401. Epub 2011 Sep 12. Oncogene. 2012. PMID: 21909140

9

RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R. Närvä E, et al. Among authors: lahdesmaki h. Stem Cells. 2012 Mar;30(3):452-60. doi: 10.1002/stem.1013. Stem Cells. 2012. PMID: 22162396 Free PMC article.

10

Chemical castration and anti-androgens induce differential gene expression in prostate cancer.

Lehmusvaara S, Erkkilä T, Urbanucci A, Waltering K, Seppälä J, Larjo A, Tuominen VJ, Isola J, Kujala P, Lähdesmäki H, Kaipia A, Tammela TLj, Visakorpi T. Lehmusvaara S, et al. Among authors: lahdesmaki h. J Pathol. 2012 Jul;227(3):336-45. doi: 10.1002/path.4027. Epub 2012 May 8. J Pathol. 2012. PMID: 22431170 Clinical Trial.

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