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Genetic schizophrenia risk variants jointly modulate total brain and white matter volume.
Terwisscha van Scheltinga AF, Bakker SC, van Haren NE, Derks EM, Buizer-Voskamp JE, Boos HB, Cahn W, Hulshoff Pol HE, Ripke S, Ophoff RA, Kahn RS; Psychiatric Genome-wide Association Study Consortium. Terwisscha van Scheltinga AF, et al. Among authors: derks em. Biol Psychiatry. 2013 Mar 15;73(6):525-31. doi: 10.1016/j.biopsych.2012.08.017. Epub 2012 Oct 3. Biol Psychiatry. 2013. PMID: 23039932 Free PMC article.
Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples.
Gladwin TE, Derks EM; Genetic Risk and Outcome of Psychosis (GROUP); Rietschel M, Mattheisen M, Breuer R, Schulze TG, Nöthen MM, Levinson D, Shi J, Gejman PV, Cichon S, Ophoff RA. Gladwin TE, et al. Among authors: derks em. PLoS One. 2012;7(6):e38828. doi: 10.1371/journal.pone.0038828. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22723893 Free PMC article.
No evidence that common genetic risk variation is shared between schizophrenia and autism.
Vorstman JA, Anney RJ, Derks EM, Gallagher L, Gill M, de Jonge MV, van Engeland H, Kahn RS, Ophoff RA; Autism Genome Project, the International Schizophrenia Consortium. Vorstman JA, et al. Among authors: derks em. Am J Med Genet B Neuropsychiatr Genet. 2013 Jan;162B(1):55-60. doi: 10.1002/ajmg.b.32121. Epub 2012 Nov 28. Am J Med Genet B Neuropsychiatr Genet. 2013. PMID: 23193033 Free article.
Schizophrenia genetic variants are not associated with intelligence.
van Scheltinga AF, Bakker SC, van Haren NE, Derks EM, Buizer-Voskamp JE, Cahn W, Ripke S; Psychiatric Genome-Wide Association Study (GWAS) Consortium; Ophoff RA, Kahn RS. van Scheltinga AF, et al. Among authors: derks em. Psychol Med. 2013 Dec;43(12):2563-70. doi: 10.1017/S0033291713000196. Epub 2013 Feb 15. Psychol Med. 2013. PMID: 23410598 Free PMC article.
A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability.
Derks EM, Ayub M, Chambert K, Del Favero J, Johnstone M, MacGregor S, Maclean A, McKechanie AG, McRae AF, Moran JL, Pickard BS, Purcell S, Sklar P, StClair DM, Wray NR, Visscher PM, Blackwood DH. Derks EM, et al. Am J Med Genet B Neuropsychiatr Genet. 2013 Dec;162B(8):847-54. doi: 10.1002/ajmg.b.32189. Epub 2013 Sep 25. Am J Med Genet B Neuropsychiatr Genet. 2013. PMID: 24115684
171 results