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Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration.
Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M. Spinelli AM, et al. Among authors: matrougui k. Pflugers Arch. 2012 Nov;464(5):481-92. doi: 10.1007/s00424-012-1160-5. Epub 2012 Sep 27. Pflugers Arch. 2012. PMID: 23014880 Free PMC article.
Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia.
González-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, Trebak M. González-Cobos JC, et al. Among authors: matrougui k. Circ Res. 2013 Mar 29;112(7):1013-25. doi: 10.1161/CIRCRESAHA.111.300220. Epub 2013 Jan 24. Circ Res. 2013. PMID: 23349245 Free PMC article.
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels.
Zhang X, González-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M. Zhang X, et al. Among authors: matrougui k. Mol Cell Biol. 2013 Sep;33(18):3715-23. doi: 10.1128/MCB.00554-13. Epub 2013 Jul 22. Mol Cell Biol. 2013. PMID: 23878392 Free PMC article.
Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.
Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M. Zhang W, et al. Among authors: matrougui k. Circ Res. 2011 Aug 19;109(5):534-42. doi: 10.1161/CIRCRESAHA.111.246777. Epub 2011 Jul 7. Circ Res. 2011. PMID: 21737791 Free PMC article.
92 results