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Inhibition of Aurora-A results in increased cell death in 3-dimensional culture microenvironment, reduced migration and is associated with enhanced radiosensitivity in human nasopharyngeal carcinoma.
Wan XB, Fan XJ, Chen MY, Xu J, Long ZJ, Hua YJ, Ji H, Liu L, Hong MH, Zeng YX, Liu Q. Wan XB, et al. Among authors: liu l, liu q. Cancer Biol Ther. 2009 Aug;8(15):1500-6. doi: 10.4161/cbt.8.15.8958. Epub 2009 Aug 8. Cancer Biol Ther. 2009. PMID: 19502819 Free article.
Aurora-A activation, correlated with hypoxia-inducible factor-1α, promotes radiochemoresistance and predicts poor outcome for nasopharyngeal carcinoma.
Wan XB, Fan XJ, Huang PY, Dong D, Zhang Y, Chen MY, Xiang J, Xu J, Liu L, Zhou WH, Lv YC, Wu XY, Hong MH, Liu Q. Wan XB, et al. Among authors: liu l, liu q. Cancer Sci. 2012 Aug;103(8):1586-94. doi: 10.1111/j.1349-7006.2012.02332.x. Epub 2012 Jul 5. Cancer Sci. 2012. PMID: 22587416 Free PMC article. Clinical Trial.
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