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Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.
Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Kopkan L, et al. Among authors: varcabova s. Kidney Blood Press Res. 2012;35(6):595-607. doi: 10.1159/000339883. Epub 2012 Aug 29. Kidney Blood Press Res. 2012. PMID: 22948718 Free PMC article.
Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.
Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Cervenka L. Sporková A, et al. Among authors: varcabova s. Am J Physiol Regul Integr Comp Physiol. 2011 Jun;300(6):R1468-75. doi: 10.1152/ajpregu.00215.2010. Epub 2011 Mar 16. Am J Physiol Regul Integr Comp Physiol. 2011. PMID: 21411763 Free PMC article.
Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Červenka L. Honetschlägerová Z, et al. Among authors: varcabova s. J Hypertens. 2013 Feb;31(2):321-32. doi: 10.1097/HJH.0b013e32835b50aa. J Hypertens. 2013. PMID: 23307303 Free PMC article.