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Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.
Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Kopkan L, et al. Among authors: tsai hj. Kidney Blood Press Res. 2012;35(6):595-607. doi: 10.1159/000339883. Epub 2012 Aug 29. Kidney Blood Press Res. 2012. PMID: 22948718 Free PMC article.
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Honetschlägerová Z, Husková Z, Vaňourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Červenka L, Kopkan L. Honetschlägerová Z, et al. Among authors: tsai hj. J Physiol. 2011 Jan 1;589(Pt 1):207-19. doi: 10.1113/jphysiol.2010.199505. J Physiol. 2011. PMID: 21078594 Free PMC article.
Soluble epoxide hydrolase inhibition modulates vascular remodeling.
Simpkins AN, Rudic RD, Roy S, Tsai HJ, Hammock BD, Imig JD. Simpkins AN, et al. Among authors: tsai hj. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H795-806. doi: 10.1152/ajpheart.00543.2009. Epub 2009 Dec 24. Am J Physiol Heart Circ Physiol. 2010. PMID: 20035028 Free PMC article.
Orally bioavailable potent soluble epoxide hydrolase inhibitors.
Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Hwang SH, et al. Among authors: tsai hj. J Med Chem. 2007 Aug 9;50(16):3825-40. doi: 10.1021/jm070270t. Epub 2007 Jul 6. J Med Chem. 2007. PMID: 17616115 Free PMC article.
723 results