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The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.
Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW Jr, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. Nunomura A, et al. Among authors: mckeel dw jr. J Neuropathol Exp Neurol. 2012 Mar;71(3):233-41. doi: 10.1097/NEN.0b013e318248e614. J Neuropathol Exp Neurol. 2012. PMID: 22318126 Free PMC article.
Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease.
Price JL, McKeel DW Jr, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. Price JL, et al. Among authors: mckeel dw jr. Neurobiol Aging. 2009 Jul;30(7):1026-36. doi: 10.1016/j.neurobiolaging.2009.04.002. Epub 2009 Apr 18. Neurobiol Aging. 2009. PMID: 19376612 Free PMC article.
Alliance of Nuclear Worker Advocacy Groups.
McKeel DW Jr, Williams H, Anderson J, Michel J, Barrie T, Barker K, Schwartz R, Merritt M; ANWAG members. McKeel DW Jr, et al. Health Phys. 2009 Feb;96(2):187-8; author reply 189. doi: 10.1097/01.HP.0000336984.08674.48. Health Phys. 2009. PMID: 19131742 No abstract available.
Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?
Clark CM, Xie S, Chittams J, Ewbank D, Peskind E, Galasko D, Morris JC, McKeel DW Jr, Farlow M, Weitlauf SL, Quinn J, Kaye J, Knopman D, Arai H, Doody RS, DeCarli C, Leight S, Lee VM, Trojanowski JQ. Clark CM, et al. Among authors: mckeel dw jr. Arch Neurol. 2003 Dec;60(12):1696-702. doi: 10.1001/archneur.60.12.1696. Arch Neurol. 2003. PMID: 14676043
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