Liu J - Search Results

1

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.

Yu D, Pendergraff H, Liu J, Kordasiewicz HB, Cleveland DW, Swayze EE, Lima WF, Crooke ST, Prakash TP, Corey DR. Yu D, et al. Among authors: liu j. Cell. 2012 Aug 31;150(5):895-908. doi: 10.1016/j.cell.2012.08.002. Cell. 2012. PMID: 22939619 Free PMC article.

2

Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism.

Hu J, Liu J, Corey DR. Hu J, et al. Among authors: liu j. Chem Biol. 2010 Nov 24;17(11):1183-8. doi: 10.1016/j.chembiol.2010.10.013. Chem Biol. 2010. PMID: 21095568 Free PMC article.

3

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.

Hu J, Gagnon KT, Liu J, Watts JK, Syeda-Nawaz J, Bennett CF, Swayze EE, Randolph J, Chattopadhyaya J, Corey DR. Hu J, et al. Among authors: liu j. Biol Chem. 2011 Apr;392(4):315-25. doi: 10.1515/BC.2011.045. Epub 2011 Feb 7. Biol Chem. 2011. PMID: 21294677 Free PMC article.

4

Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing.

Liu J, Hu J, Corey DR. Liu J, et al. Nucleic Acids Res. 2012 Feb;40(3):1240-50. doi: 10.1093/nar/gkr780. Epub 2011 Sep 23. Nucleic Acids Res. 2012. PMID: 21948593 Free PMC article.

5

Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway.

Hu J, Liu J, Yu D, Chu Y, Corey DR. Hu J, et al. Among authors: liu j. Nucleic Acids Res. 2012 Dec;40(22):11270-80. doi: 10.1093/nar/gks907. Epub 2012 Oct 4. Nucleic Acids Res. 2012. PMID: 23042244 Free PMC article.

6

RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression.

Liu J, Pendergraff H, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Hu J, Corey DR. Liu J, et al. Nucleic Acids Res. 2013 Oct;41(18):8788-801. doi: 10.1093/nar/gkt594. Epub 2013 Jul 24. Nucleic Acids Res. 2013. PMID: 23887934 Free PMC article.

7

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.

Liu J, Yu D, Aiba Y, Pendergraff H, Swayze EE, Lima WF, Hu J, Prakash TP, Corey DR. Liu J, et al. Nucleic Acids Res. 2013 Nov;41(20):9570-83. doi: 10.1093/nar/gkt693. Epub 2013 Aug 9. Nucleic Acids Res. 2013. PMID: 23935115 Free PMC article.

8

Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions.

Aiba Y, Hu J, Liu J, Xiang Q, Martinez C, Corey DR. Aiba Y, et al. Among authors: liu j. Biochemistry. 2013 Dec 23;52(51):9329-38. doi: 10.1021/bi4014209. Epub 2013 Nov 27. Biochemistry. 2013. PMID: 24266403 Free PMC article.

9

Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.

Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR. Hu J, et al. Among authors: liu j. Nucleic Acid Ther. 2014 Jun;24(3):199-209. doi: 10.1089/nat.2013.0476. Epub 2014 Apr 2. Nucleic Acid Ther. 2014. PMID: 24694346 Free PMC article.

10

Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs.

Hu J, Liu J, Narayanannair KJ, Lackey JG, Kuchimanchi S, Rajeev KG, Manoharan M, Swayze EE, Lima WF, Prakash TP, Xiang Q, Martinez C, Corey DR. Hu J, et al. Among authors: liu j. Biochemistry. 2014 Jul 22;53(28):4510-8. doi: 10.1021/bi500610r. Epub 2014 Jul 11. Biochemistry. 2014. PMID: 24981774 Free PMC article.

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