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Overexpression of vesicle-associated membrane protein (VAMP) 3, but not VAMP2, protects glucose transporter (GLUT) 4 protein translocation in an in vitro model of cardiac insulin resistance.
Schwenk RW, Angin Y, Steinbusch LK, Dirkx E, Hoebers N, Coumans WA, Bonen A, Broers JL, van Eys GJ, Glatz JF, Luiken JJ. Schwenk RW, et al. Among authors: steinbusch lk. J Biol Chem. 2012 Oct 26;287(44):37530-9. doi: 10.1074/jbc.M112.363630. Epub 2012 Aug 30. J Biol Chem. 2012. PMID: 22936810 Free PMC article.
Absence of fatty acid transporter CD36 protects against Western-type diet-related cardiac dysfunction following pressure overload in mice.
Steinbusch LK, Luiken JJ, Vlasblom R, Chabowski A, Hoebers NT, Coumans WA, Vroegrijk IO, Voshol PJ, Ouwens DM, Glatz JF, Diamant M. Steinbusch LK, et al. Am J Physiol Endocrinol Metab. 2011 Oct;301(4):E618-27. doi: 10.1152/ajpendo.00106.2011. Epub 2011 Jun 28. Am J Physiol Endocrinol Metab. 2011. PMID: 21712535 Free article.
CD36 as a target to prevent cardiac lipotoxicity and insulin resistance.
Glatz JF, Angin Y, Steinbusch LK, Schwenk RW, Luiken JJ. Glatz JF, et al. Among authors: steinbusch lk. Prostaglandins Leukot Essent Fatty Acids. 2013 Jan;88(1):71-7. doi: 10.1016/j.plefa.2012.04.009. Epub 2012 May 12. Prostaglandins Leukot Essent Fatty Acids. 2013. PMID: 22580174 Free article.
Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance.
Dirkx E, van Eys GJ, Schwenk RW, Steinbusch LK, Hoebers N, Coumans WA, Peters T, Janssen BJ, Brans B, Vogg AT, Neumann D, Glatz JF, Luiken JJ. Dirkx E, et al. Among authors: steinbusch lk. J Mol Cell Cardiol. 2014 Nov;76:208-17. doi: 10.1016/j.yjmcc.2014.08.017. Epub 2014 Aug 28. J Mol Cell Cardiol. 2014. PMID: 25173922
CD36 is important for adipocyte recruitment and affects lipolysis.
Vroegrijk IO, van Klinken JB, van Diepen JA, van den Berg SA, Febbraio M, Steinbusch LK, Glatz JF, Havekes LM, Voshol PJ, Rensen PC, van Dijk KW, van Harmelen V. Vroegrijk IO, et al. Among authors: steinbusch lk. Obesity (Silver Spring). 2013 Oct;21(10):2037-45. doi: 10.1002/oby.20354. Epub 2013 May 29. Obesity (Silver Spring). 2013. PMID: 23512311 Free article.
18 results