Dessauer CW - Search Results

1

The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum.

Xie K, Masuho I, Brand C, Dessauer CW, Martemyanov KA. Xie K, et al. Among authors: dessauer cw. Sci Signal. 2012 Aug 28;5(239):ra63. doi: 10.1126/scisignal.2002922. Sci Signal. 2012. PMID: 22932702 Free PMC article.

2

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes.

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Annett S, Boison D, Burns KE, Dessauer C, Gertsch J, Helsby NA, Izzo AA, Ostrom R, Papapetropoulos A, Pyne NJ, Pyne S, Robson T, Seifert R, Stasch JP, Szabo C, van der Stelt M, van der Vliet A, Watts V, Wong SS. Alexander SPH, et al. Br J Pharmacol. 2023 Oct;180 Suppl 2:S289-S373. doi: 10.1111/bph.16181. Br J Pharmacol. 2023. PMID: 38123154 Free article. Review.

3

Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production.

Pulliainen AT, Pieles K, Brand CS, Hauert B, Böhm A, Quebatte M, Wepf A, Gstaiger M, Aebersold R, Dessauer CW, Dehio C. Pulliainen AT, et al. Among authors: dessauer cw. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9581-6. doi: 10.1073/pnas.1117651109. Epub 2012 May 25. Proc Natl Acad Sci U S A. 2012. PMID: 22635269 Free PMC article.

4

Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds.

Brand CS, Hocker HJ, Gorfe AA, Cavasotto CN, Dessauer CW. Brand CS, et al. Among authors: dessauer cw. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75. doi: 10.1124/jpet.113.208157. Epub 2013 Sep 4. J Pharmacol Exp Ther. 2013. PMID: 24006339 Free PMC article.

5

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor.

Conley JM, Brand CS, Bogard AS, Pratt EP, Xu R, Hockerman GH, Ostrom RS, Dessauer CW, Watts VJ. Conley JM, et al. Among authors: dessauer cw. J Pharmacol Exp Ther. 2013 Nov;347(2):276-87. doi: 10.1124/jpet.113.207449. Epub 2013 Sep 5. J Pharmacol Exp Ther. 2013. PMID: 24008337 Free PMC article.

6

Adenylyl Cyclase 5 Regulation by Gβγ Involves Isoform-Specific Use of Multiple Interaction Sites.

Brand CS, Sadana R, Malik S, Smrcka AV, Dessauer CW. Brand CS, et al. Among authors: dessauer cw. Mol Pharmacol. 2015 Oct;88(4):758-67. doi: 10.1124/mol.115.099556. Epub 2015 Jul 23. Mol Pharmacol. 2015. PMID: 26206488 Free PMC article.

7

Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling.

Xie K, Masuho I, Shih CC, Cao Y, Sasaki K, Lai CW, Han PL, Ueda H, Dessauer CW, Ehrlich ME, Xu B, Willardson BM, Martemyanov KA. Xie K, et al. Among authors: dessauer cw. Elife. 2015 Nov 27;4:e10451. doi: 10.7554/eLife.10451. Elife. 2015. PMID: 26613416 Free PMC article.

8

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.

Brust TF, Alongkronrusmee D, Soto-Velasquez M, Baldwin TA, Ye Z, Dai M, Dessauer CW, van Rijn RM, Watts VJ. Brust TF, et al. Among authors: dessauer cw. Sci Signal. 2017 Feb 21;10(467):eaah5381. doi: 10.1126/scisignal.aah5381. Sci Signal. 2017. PMID: 28223412 Free PMC article.

9

Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction.

Li Y, Baldwin TA, Wang Y, Subramaniam J, Carbajal AG, Brand CS, Cunha SR, Dessauer CW. Li Y, et al. Among authors: dessauer cw. Sci Rep. 2017 Jul 17;7(1):5522. doi: 10.1038/s41598-017-05816-w. Sci Rep. 2017. PMID: 28717248 Free PMC article.

10

Insights into the Regulatory Properties of Human Adenylyl Cyclase Type 9.

Baldwin TA, Li Y, Brand CS, Watts VJ, Dessauer CW. Baldwin TA, et al. Among authors: dessauer cw. Mol Pharmacol. 2019 Apr;95(4):349-360. doi: 10.1124/mol.118.114595. Epub 2019 Jan 29. Mol Pharmacol. 2019. PMID: 30696718 Free PMC article.

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