Carballeira NM - Search Results

1

2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.

Carballeira NM, Cartagena M, Sanabria D, Tasdemir D, Prada CF, Reguera RM, Balaña-Fouce R. Carballeira NM, et al. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6185-9. doi: 10.1016/j.bmcl.2012.08.019. Epub 2012 Aug 10. Bioorg Med Chem Lett. 2012. PMID: 22932312 Free PMC article.

2

First total synthesis and antiprotozoal activity of (Z)-17-methyl-13-octadecenoic acid, a new marine fatty acid from the sponge Polymastia penicillus.

Carballeira NM, Montano N, Balaña-Fouce R, Prada CF. Carballeira NM, et al. Chem Phys Lipids. 2009 Sep;161(1):38-43. doi: 10.1016/j.chemphyslip.2009.06.140. Epub 2009 Jun 13. Chem Phys Lipids. 2009. PMID: 19527698 Free PMC article.

3

Total synthesis and antileishmanial activity of the natural occurring acetylenic fatty acids 6-heptadecynoic acid and 6-icosynoic acid.

Carballeira NM, Cartagena MM, Prada CF, Rubio CF, Balaña-Fouce R. Carballeira NM, et al. Lipids. 2009 Oct;44(10):953-61. doi: 10.1007/s11745-009-3345-z. Epub 2009 Sep 30. Lipids. 2009. PMID: 19789903 Free PMC article.

4

First total synthesis and antileishmanial activity of (Z)-16-methyl-11-heptadecenoic acid, a new marine fatty acid from the sponge Dragmaxia undata.

Carballeira NM, Montano N, Cintrón GA, Márquez C, Rubio CF, Prada CF, Balaña-Fouce R. Carballeira NM, et al. Chem Phys Lipids. 2011 Feb;164(2):113-7. doi: 10.1016/j.chemphyslip.2010.11.006. Epub 2010 Dec 1. Chem Phys Lipids. 2011. PMID: 21129369 Free PMC article.

5

First total synthesis of the (±)-2-methoxy-6-heptadecynoic acid and related 2-methoxylated analogs as effective inhibitors of the leishmania topoisomerase IB enzyme.

Carballeira NM, Cartagena M, Li F, Chen Z, Prada CF, Calvo-Alvarez E, Reguera RM, Balaña-Fouce R. Carballeira NM, et al. Pure Appl Chem. 2012;84(9):1867-1875. doi: 10.1351/PAC-CON-11-10-21. Epub 2012 Apr 29. Pure Appl Chem. 2012. PMID: 23118491 Free PMC article.

6

Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from Leishmania donovani with a mechanism different from that of camptothecin.

Carballeira NM, Montano N, Alvarez-Velilla R, Prada CF, Reguera RM, Balaña-Fouce R. Carballeira NM, et al. Mar Drugs. 2013 Sep 30;11(10):3661-75. doi: 10.3390/md11103661. Mar Drugs. 2013. PMID: 24084785 Free PMC article.

7

2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes.

Carballeira NM, Bwalya AG, Itoe MA, Andricopulo AD, Cordero-Maldonado ML, Kaiser M, Mota MM, Crawford AD, Guido RV, Tasdemir D. Carballeira NM, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4151-7. doi: 10.1016/j.bmcl.2014.07.050. Epub 2014 Jul 24. Bioorg Med Chem Lett. 2014. PMID: 25103602 Free PMC article.

8

Novel Very Long-Chain α-Methoxylated Δ5,9 Fatty Acids from the Sponge Asteropus niger Are Effective Inhibitors of Topoisomerases IB.

Carballeira NM, Montano N, Amador LA, Rodríguez AD, Golovko MY, Golovko SA, Reguera RM, Álvarez-Velilla R, Balaña-Fouce R. Carballeira NM, et al. Lipids. 2016 Feb;51(2):245-56. doi: 10.1007/s11745-015-4114-9. Epub 2015 Dec 22. Lipids. 2016. PMID: 26694606 Free PMC article.

9

First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties.

Carballeira NM, Morales-Guzman C, Alvarez-Benedicto E, Torres-Martinez Z, Delgado Y, Griebenow KH, Tinoco AD, Reguera RM, Perez-Pertejo Y, Carbajo-Andres R, Balana-Fouce R. Carballeira NM, et al. Curr Top Med Chem. 2018;18(5):418-427. doi: 10.2174/1568026618666180516125056. Curr Top Med Chem. 2018. PMID: 29766807 Free PMC article.

10

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.

Tasdemir D, Sanabria D, Lauinger IL, Tarun A, Herman R, Perozzo R, Zloh M, Kappe SH, Brun R, Carballeira NM. Tasdemir D, et al. Among authors: carballeira nm. Bioorg Med Chem. 2010 Nov 1;18(21):7475-85. doi: 10.1016/j.bmc.2010.08.055. Epub 2010 Sep 18. Bioorg Med Chem. 2010. PMID: 20855214 Free PMC article.

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