García P - Search Results

1

MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.

Clarke M, Dumon S, Ward C, Jäger R, Freeman S, Dawood B, Sheriff L, Lorvellec M, Kralovics R, Frampton J, García P. Clarke M, et al. Among authors: garcia p. Leukemia. 2013 Mar;27(3):661-70. doi: 10.1038/leu.2012.241. Epub 2012 Aug 22. Leukemia. 2013. PMID: 22910183 Free PMC article.

2

Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.

Clarke M, Volpe G, Sheriff L, Walton D, Ward C, Wei W, Dumon S, García P, Frampton J. Clarke M, et al. Among authors: garcia p. Leukemia. 2017 Apr;31(4):957-966. doi: 10.1038/leu.2016.289. Epub 2016 Oct 17. Leukemia. 2017. PMID: 27748374 Free PMC article.

3

The transcription factor B-Myb is essential for S-phase progression and genomic stability in diploid and polyploid megakaryocytes.

García P, Frampton J. García P, et al. J Cell Sci. 2006 Apr 15;119(Pt 8):1483-93. doi: 10.1242/jcs.02870. Epub 2006 Mar 21. J Cell Sci. 2006. PMID: 16551698

4

B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cells.

Lorvellec M, Dumon S, Maya-Mendoza A, Jackson D, Frampton J, García P. Lorvellec M, et al. Among authors: garcia p. Stem Cells. 2010 Oct;28(10):1751-9. doi: 10.1002/stem.496. Stem Cells. 2010. PMID: 20715180 Free PMC article.

5

MYBL2 Supports DNA Double Strand Break Repair in Hematopoietic Stem Cells.

Bayley R, Blakemore D, Cancian L, Dumon S, Volpe G, Ward C, Almaghrabi R, Gujar J, Reeve N, Raghavan M, Higgs MR, Stewart GS, Petermann E, García P. Bayley R, et al. Among authors: garcia p. Cancer Res. 2018 Oct 15;78(20):5767-5779. doi: 10.1158/0008-5472.CAN-18-0273. Epub 2018 Aug 6. Cancer Res. 2018. PMID: 30082276

6

MYBL2 amplification in breast cancer: Molecular mechanisms and therapeutic potential.

Bayley R, Ward C, Garcia P. Bayley R, et al. Among authors: garcia p. Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188407. doi: 10.1016/j.bbcan.2020.188407. Epub 2020 Aug 25. Biochim Biophys Acta Rev Cancer. 2020. PMID: 32853735 Review.

7

C/EBPα and MYB regulate FLT3 expression in AML.

Volpe G, Walton DS, Del Pozzo W, Garcia P, Dassé E, O'Neill LP, Griffiths M, Frampton J, Dumon S. Volpe G, et al. Among authors: garcia p. Leukemia. 2013 Jul;27(7):1487-96. doi: 10.1038/leu.2013.23. Epub 2013 Jan 23. Leukemia. 2013. PMID: 23340802 Free PMC article.

8

Generation of a conditional allele of the B-myb gene.

García P, Berlanga O, Watson R, Frampton J. García P, et al. Genesis. 2005 Dec;43(4):189-95. doi: 10.1002/gene.20170. Genesis. 2005. PMID: 16283626

9

Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor.

García P, Frampton J. García P, et al. Dev Cell. 2008 Jun;14(6):815-6. doi: 10.1016/j.devcel.2008.05.011. Dev Cell. 2008. PMID: 18539110 Free article.

10

Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis.

García P, Clarke M, Vegiopoulos A, Berlanga O, Camelo A, Lorvellec M, Frampton J. García P, et al. EMBO J. 2009 May 20;28(10):1492-504. doi: 10.1038/emboj.2009.97. Epub 2009 Apr 9. EMBO J. 2009. PMID: 19360001 Free PMC article.

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