Kahn ML - Search Results

1

Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth.

Zheng X, Xu C, Smith AO, Stratman AN, Zou Z, Kleaveland B, Yuan L, Didiku C, Sen A, Liu X, Skuli N, Zaslavsky A, Chen M, Cheng L, Davis GE, Kahn ML. Zheng X, et al. Among authors: kahn ml. Dev Cell. 2012 Aug 14;23(2):342-55. doi: 10.1016/j.devcel.2012.06.004. Dev Cell. 2012. PMID: 22898778 Free PMC article.

2

In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines.

Chen H, Zou Z, Sarratt KL, Zhou D, Zhang M, Sebzda E, Hammer DA, Kahn ML. Chen H, et al. Among authors: kahn ml. Genes Dev. 2006 Apr 15;20(8):927-32. doi: 10.1101/gad.1408306. Genes Dev. 2006. PMID: 16618804 Free PMC article.

3

Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.

Abtahian F, Bezman N, Clemens R, Sebzda E, Cheng L, Shattil SJ, Kahn ML, Koretzky GA. Abtahian F, et al. Among authors: kahn ml. Mol Cell Biol. 2006 Sep;26(18):6936-49. doi: 10.1128/MCB.01040-06. Mol Cell Biol. 2006. PMID: 16943434 Free PMC article.

4

Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development.

Sebzda E, Hibbard C, Sweeney S, Abtahian F, Bezman N, Clemens G, Maltzman JS, Cheng L, Liu F, Turner M, Tybulewicz V, Koretzky GA, Kahn ML. Sebzda E, et al. Among authors: kahn ml. Dev Cell. 2006 Sep;11(3):349-61. doi: 10.1016/j.devcel.2006.07.007. Dev Cell. 2006. PMID: 16950126 Free article.

5

Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML. Lee JS, et al. Among authors: kahn ml. Dev Cell. 2006 Dec;11(6):845-57. doi: 10.1016/j.devcel.2006.09.006. Dev Cell. 2006. PMID: 17141159 Free article.

6

Structure-function analysis reveals discrete beta3 integrin inside-out and outside-in signaling pathways in platelets.

Zou Z, Chen H, Schmaier AA, Hynes RO, Kahn ML. Zou Z, et al. Among authors: kahn ml. Blood. 2007 Apr 15;109(8):3284-90. doi: 10.1182/blood-2006-10-051664. Epub 2006 Dec 14. Blood. 2007. PMID: 17170121 Free article.

7

Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns.

Sebzda E, Zou Z, Lee JS, Wang T, Kahn ML. Sebzda E, et al. Among authors: kahn ml. Nat Immunol. 2008 Mar;9(3):292-300. doi: 10.1038/ni1565. Epub 2008 Feb 3. Nat Immunol. 2008. PMID: 18246069

8

Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.

Miller MW, Basra S, Kulp DW, Billings PC, Choi S, Beavers MP, McCarty OJ, Zou Z, Kahn ML, Bennett JS, DeGrado WF. Miller MW, et al. Among authors: kahn ml. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):719-24. doi: 10.1073/pnas.0811622106. Epub 2009 Jan 13. Proc Natl Acad Sci U S A. 2009. PMID: 19141632 Free PMC article.

9

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.

Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. Kleaveland B, et al. Among authors: kahn ml. Nat Med. 2009 Feb;15(2):169-76. doi: 10.1038/nm.1918. Epub 2009 Jan 18. Nat Med. 2009. PMID: 19151727 Free PMC article.

10

Negative regulation of activated alpha-2 integrins during thrombopoiesis.

Zou Z, Schmaier AA, Cheng L, Mericko P, Dickeson SK, Stricker TP, Santoro SA, Kahn ML. Zou Z, et al. Among authors: kahn ml. Blood. 2009 Jun 18;113(25):6428-39. doi: 10.1182/blood-2008-08-175356. Epub 2009 Mar 3. Blood. 2009. PMID: 19258597 Free article.

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