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Page 1
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.
Holzinger D, Gieldon L, Mysore V, Nippe N, Taxman DJ, Duncan JA, Broglie PM, Marketon K, Austermann J, Vogl T, Foell D, Niemann S, Peters G, Roth J, Löffler B. Holzinger D, et al. Among authors: austermann j. J Leukoc Biol. 2012 Nov;92(5):1069-81. doi: 10.1189/jlb.0112014. Epub 2012 Aug 14. J Leukoc Biol. 2012. PMID: 22892107 Free PMC article.
MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes.
Wittkowski H, Kuemmerle-Deschner JB, Austermann J, Holzinger D, Goldbach-Mansky R, Gramlich K, Lohse P, Jung T, Roth J, Benseler SM, Foell D. Wittkowski H, et al. Among authors: austermann j. Ann Rheum Dis. 2011 Dec;70(12):2075-2081. doi: 10.1136/ard.2011.152496. Epub 2011 Sep 8. Ann Rheum Dis. 2011. PMID: 21908452 Free PMC article.
Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions.
Austermann J, Friesenhagen J, Fassl SK, Petersen B, Ortkras T, Burgmann J, Barczyk-Kahlert K, Faist E, Zedler S, Pirr S, Rohde C, Müller-Tidow C, von Köckritz-Blickwede M, von Kaisenberg CS, Flohé SB, Ulas T, Schultze JL, Roth J, Vogl T, Viemann D. Austermann J, et al. Cell Rep. 2014 Dec 24;9(6):2112-23. doi: 10.1016/j.celrep.2014.11.020. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497086 Free article.
Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Fassl SK, et al. Among authors: austermann j. J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505274 Clinical Trial.
Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.
Holzinger D, Fassl SK, de Jager W, Lohse P, Röhrig UF, Gattorno M, Omenetti A, Chiesa S, Schena F, Austermann J, Vogl T, Kuhns DB, Holland SM, Rodríguez-Gallego C, López-Almaraz R, Arostegui JI, Colino E, Roldan R, Fessatou S, Isidor B, Poignant S, Ito K, Epple HJ, Bernstein JA, Jeng M, Frankovich J, Lionetti G, Church JA, Ong PY, LaPlant M, Abinun M, Skinner R, Bigley V, Sachs UJ, Hinze C, Hoppenreijs E, Ehrchen J, Foell D, Chae JJ, Ombrello A, Aksentijevich I, Sunderkoetter C, Roth J. Holzinger D, et al. Among authors: austermann j. J Allergy Clin Immunol. 2015 Nov;136(5):1337-45. doi: 10.1016/j.jaci.2015.04.016. Epub 2015 May 27. J Allergy Clin Immunol. 2015. PMID: 26025129 Free PMC article.
S100-alarmins: potential therapeutic targets for arthritis.
Austermann J, Zenker S, Roth J. Austermann J, et al. Expert Opin Ther Targets. 2017 Jul;21(7):739-751. doi: 10.1080/14728222.2017.1330411. Epub 2017 May 25. Expert Opin Ther Targets. 2017. PMID: 28494625 Review.
S100 proteins in rheumatic diseases.
Austermann J, Spiekermann C, Roth J. Austermann J, et al. Nat Rev Rheumatol. 2018 Sep;14(9):528-541. doi: 10.1038/s41584-018-0058-9. Nat Rev Rheumatol. 2018. PMID: 30076385 Review.
Signaling mechanisms inducing hyporesponsiveness of phagocytes during systemic inflammation.
Freise N, Burghard A, Ortkras T, Daber N, Imam Chasan A, Jauch SL, Fehler O, Hillebrand J, Schakaki M, Rojas J, Grimbacher B, Vogl T, Hoffmeier A, Martens S, Roth J, Austermann J. Freise N, et al. Among authors: austermann j. Blood. 2019 Jul 11;134(2):134-146. doi: 10.1182/blood.2019000320. Epub 2019 May 10. Blood. 2019. PMID: 31076441 Free article.
45 results