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Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.
Taskinen MR, Adiels M, Westerbacka J, Söderlund S, Kahri J, Lundbom N, Lundbom J, Hakkarainen A, Olofsson SO, Orho-Melander M, Borén J. Taskinen MR, et al. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2144-50. doi: 10.1161/ATVBAHA.111.224808. Epub 2011 Jul 21. Arterioscler Thromb Vasc Biol. 2011. PMID: 21778423
The IRS1 rs2943641 variant and risk of future cancer among morbidly obese individuals.
Maglio C, Ericson U, Burza MA, Mancina RM, Pirazzi C, Assarsson JA, Sjöholm K, Baroni MG, Svensson PA, Montalcini T, Pujia A, Sjöström L, Wiklund O, Carlsson LM, Borén J, Orho-Melander M, Romeo S. Maglio C, et al. J Clin Endocrinol Metab. 2013 Apr;98(4):E785-9. doi: 10.1210/jc.2012-2831. Epub 2013 Feb 15. J Clin Endocrinol Metab. 2013. PMID: 23418314
Genetic variation in SULF2 is associated with postprandial clearance of triglyceride-rich remnant particles and triglyceride levels in healthy subjects.
Matikainen N, Burza MA, Romeo S, Hakkarainen A, Adiels M, Folkersen L, Eriksson P, Lundbom N, Ehrenborg E, Orho-Melander M, Taskinen MR, Borén J. Matikainen N, et al. PLoS One. 2013 Nov 20;8(11):e79473. doi: 10.1371/journal.pone.0079473. eCollection 2013. PLoS One. 2013. PMID: 24278138 Free PMC article. Clinical Trial.
A population-based study on the prevalence of NASH using scores validated against liver histology.
Hyysalo J, Männistö VT, Zhou Y, Arola J, Kärjä V, Leivonen M, Juuti A, Jaser N, Lallukka S, Käkelä P, Venesmaa S, Simonen M, Saltevo J, Moilanen L, Korpi-Hyövalti E, Keinänen-Kiukaanniemi S, Oksa H, Orho-Melander M, Valenti L, Fargion S, Pihlajamäki J, Peltonen M, Yki-Järvinen H. Hyysalo J, et al. J Hepatol. 2014 Apr;60(4):839-46. doi: 10.1016/j.jhep.2013.12.009. Epub 2013 Dec 12. J Hepatol. 2014. PMID: 24333862
337 results