Mullen AR - Search Results

1

Genetically-defined metabolic reprogramming in cancer.

Mullen AR, DeBerardinis RJ. Mullen AR, et al. Trends Endocrinol Metab. 2012 Nov;23(11):552-9. doi: 10.1016/j.tem.2012.06.009. Epub 2012 Jul 31. Trends Endocrinol Metab. 2012. PMID: 22858391 Free PMC article. Review.

2

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Nature. 2011 Nov 20;481(7381):385-8. doi: 10.1038/nature10642. Nature. 2011. PMID: 22101431 Free PMC article.

3

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Cell Rep. 2014 Jun 12;7(5):1679-1690. doi: 10.1016/j.celrep.2014.04.037. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857658 Free PMC article.

4

Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction.

Cetinbas N, Daugaard M, Mullen AR, Hajee S, Rotblat B, Lopez A, Li A, DeBerardinis RJ, Sorensen PH. Cetinbas N, et al. Among authors: mullen ar. Oncogene. 2015 Jul 23;34(30):4005-10. doi: 10.1038/onc.2014.316. Epub 2014 Oct 6. Oncogene. 2015. PMID: 25284589 Free PMC article.

5

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.

Cheng T, Sudderth J, Yang C, Mullen AR, Jin ES, Matés JM, DeBerardinis RJ. Cheng T, et al. Among authors: mullen ar. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8674-9. doi: 10.1073/pnas.1016627108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555572 Free PMC article.

6

Glutamine: pleiotropic roles in tumor growth and stress resistance.

Shanware NP, Mullen AR, DeBerardinis RJ, Abraham RT. Shanware NP, et al. Among authors: mullen ar. J Mol Med (Berl). 2011 Mar;89(3):229-36. doi: 10.1007/s00109-011-0731-9. Epub 2011 Feb 8. J Mol Med (Berl). 2011. PMID: 21301794 Review.

7

Metabolic changes in cancer cells upon suppression of MYC.

Anso E, Mullen AR, Felsher DW, Matés JM, Deberardinis RJ, Chandel NS. Anso E, et al. Among authors: mullen ar. Cancer Metab. 2013 Feb 4;1(1):7. doi: 10.1186/2049-3002-1-7. Cancer Metab. 2013. PMID: 24280108 Free PMC article.

8

N-Acetyl cysteine abrogates silver-induced reactive oxygen species in human cells without altering silver-based antimicrobial activity.

Shah KN, Shah PN, Mullen AR, Chen Q, Southerland MR, Chirra B, DeBerardinis RJ, Cannon CL. Shah KN, et al. Among authors: mullen ar. Toxicol Lett. 2020 Oct 10;332:118-129. doi: 10.1016/j.toxlet.2020.07.014. Epub 2020 Jul 10. Toxicol Lett. 2020. PMID: 32659471 Free PMC article.

9

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

Sullivan LB, Martinez-Garcia E, Nguyen H, Mullen AR, Dufour E, Sudarshan S, Licht JD, Deberardinis RJ, Chandel NS. Sullivan LB, et al. Among authors: mullen ar. Mol Cell. 2013 Jul 25;51(2):236-48. doi: 10.1016/j.molcel.2013.05.003. Epub 2013 Jun 6. Mol Cell. 2013. PMID: 23747014 Free PMC article.

10

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development.

Hamanaka RB, Glasauer A, Hoover P, Yang S, Blatt H, Mullen AR, Getsios S, Gottardi CJ, DeBerardinis RJ, Lavker RM, Chandel NS. Hamanaka RB, et al. Among authors: mullen ar. Sci Signal. 2013 Feb 5;6(261):ra8. doi: 10.1126/scisignal.2003638. Sci Signal. 2013. PMID: 23386745 Free PMC article.

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