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Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Khalili JS, Liu S, Rodríguez-Cruz TG, Whittington M, Wardell S, Liu C, Zhang M, Cooper ZA, Frederick DT, Li Y, Zhang M, Joseph RW, Bernatchez C, Ekmekcioglu S, Grimm E, Radvanyi LG, Davis RE, Davies MA, Wargo JA, Hwu P, Lizée G. Khalili JS, et al. Among authors: whittington m. Clin Cancer Res. 2012 Oct 1;18(19):5329-40. doi: 10.1158/1078-0432.CCR-12-1632. Epub 2012 Jul 31. Clin Cancer Res. 2012. PMID: 22850568 Free PMC article.
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.
Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, Woodman SE, Davies MA, Radvanyi LG, Overwijk WW, Lizée G, Hwu P. Liu C, et al. Among authors: whittington m. Clin Cancer Res. 2013 Jan 15;19(2):393-403. doi: 10.1158/1078-0432.CCR-12-1626. Epub 2012 Nov 30. Clin Cancer Res. 2013. PMID: 23204132 Free PMC article.
BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma.
Bradley SD, Chen Z, Melendez B, Talukder A, Khalili JS, Rodriguez-Cruz T, Liu S, Whittington M, Deng W, Li F, Bernatchez C, Radvanyi LG, Davies MA, Hwu P, Lizée G. Bradley SD, et al. Among authors: whittington m. Cancer Immunol Res. 2015 Jun;3(6):602-9. doi: 10.1158/2326-6066.CIR-15-0030. Epub 2015 Mar 20. Cancer Immunol Res. 2015. PMID: 25795007 Free PMC article.
Valuing the Societal Impact of Medicines and Other Health Technologies: A User Guide to Current Best Practices.
Shafrin J, Kim J, Cohen JT, Garrison LP, Goldman DA, Doshi JA, Krieger J, Lakdawalla DN, Neumann PJ, Phelps CE, Whittington MD, Willke R. Shafrin J, et al. Among authors: whittington md. Forum Health Econ Policy. 2024 Nov 8;27(1):29-116. doi: 10.1515/fhep-2024-0014. eCollection 2024 Jun 1. Forum Health Econ Policy. 2024. PMID: 39512185 Free PMC article.
KarXT for schizophrenia-effectiveness and value: A summary from the Institute for Clinical and Economic Review's New England Comparative Effectiveness Public Advisory Council.
McKenna A, Tice JA, Whittington MD, Wright AC, Richardson M, Raymond FR, Pearson SD, Rind DM, Agboola F. McKenna A, et al. Among authors: whittington md. J Manag Care Spec Pharm. 2024 Jun;30(6):624-628. doi: 10.18553/jmcp.2024.30.6.624. J Manag Care Spec Pharm. 2024. PMID: 38824622 Free PMC article. No abstract available.
The effectiveness and value of sotatercept for pulmonary arterial hypertension: A summary from the Institute for Clinical and Economic Review's Midwest Comparative Effectiveness Public Advisory Council.
Nikitin D, Lin GA, Whittington MD, Nhan E, Kayali Y, Rind DM, Pearson SD, Agboola F. Nikitin D, et al. Among authors: whittington md. J Manag Care Spec Pharm. 2024 May;30(5):491-495. doi: 10.18553/jmcp.2024.30.5.491. J Manag Care Spec Pharm. 2024. PMID: 38701024 Free PMC article. No abstract available.
250 results