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An anionic synthetic sugar containing 6-SO3 -NAcGlc mimics the sulfated cruzipain epitope that plays a central role in immune recognition.
Couto AS, Soprano LL, Landoni M, Pourcelot M, Acosta DM, Bultel L, Parente J, Ferrero MR, Barbier M, Dussouy C, Esteva MI, Kovensky J, Duschak VG. Couto AS, et al. Among authors: dussouy c. FEBS J. 2012 Oct;279(19):3665-3679. doi: 10.1111/j.1742-4658.2012.08728.x. Epub 2012 Sep 4. FEBS J. 2012. PMID: 22846255 Free article.
Access to Galectin-3 Inhibitors from Chemoenzymatic Synthons.
Dussouy C, Téletchéa S, Lambert A, Charlier C, Botez I, De Ceuninck F, Grandjean C. Dussouy C, et al. J Org Chem. 2020 Dec 18;85(24):16099-16114. doi: 10.1021/acs.joc.0c01927. Epub 2020 Nov 17. J Org Chem. 2020. PMID: 33200927
Development of a Sensitive Microarray Platform for the Ranking of Galectin Inhibitors: Identification of a Selective Galectin-3 Inhibitor.
Dion J, Advedissian T, Storozhylova N, Dahbi S, Lambert A, Deshayes F, Viguier M, Tellier C, Poirier F, Téletchéa S, Dussouy C, Tateno H, Hirabayashi J, Grandjean C. Dion J, et al. Among authors: dussouy c. Chembiochem. 2017 Dec 14;18(24):2428-2440. doi: 10.1002/cbic.201700544. Epub 2017 Nov 20. Chembiochem. 2017. PMID: 29024281