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Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.
Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. Rozenblatt-Rosen O, et al. Among authors: kieff e. Nature. 2012 Jul 26;487(7408):491-5. doi: 10.1038/nature11288. Nature. 2012. PMID: 22810586 Free PMC article.
Viral perturbations of host networks reflect disease etiology.
Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL. Gulbahce N, et al. Among authors: kieff e. PLoS Comput Biol. 2012;8(6):e1002531. doi: 10.1371/journal.pcbi.1002531. Epub 2012 Jun 28. PLoS Comput Biol. 2012. PMID: 22761553 Free PMC article.
Epstein-Barr virus and virus human protein interaction maps.
Calderwood MA, Venkatesan K, Xing L, Chase MR, Vazquez A, Holthaus AM, Ewence AE, Li N, Hirozane-Kishikawa T, Hill DE, Vidal M, Kieff E, Johannsen E. Calderwood MA, et al. Among authors: kieff e. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7606-11. doi: 10.1073/pnas.0702332104. Epub 2007 Apr 19. Proc Natl Acad Sci U S A. 2007. PMID: 17446270 Free PMC article.
Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1.
Lee S, Sakakibara S, Maruo S, Zhao B, Calderwood MA, Holthaus AM, Lai CY, Takada K, Kieff E, Johannsen E. Lee S, et al. Among authors: kieff e. J Virol. 2009 Dec;83(23):12368-77. doi: 10.1128/JVI.01403-09. Epub 2009 Sep 23. J Virol. 2009. PMID: 19776126 Free PMC article.
Complementation with relatively large EBNA3C deletion mutants identified amino acids (aa) 1 to 506 (which includes the RBP-Jkappa/CSL [RBP-Jkappa] binding domain) and 733 to 909 to be essential for LCL growth, aa 728 to 732 and 910 to 992 to be important for full wild-type (wt) g …
Complementation with relatively large EBNA3C deletion mutants identified amino acids (aa) 1 to 506 (which includes the RBP-Jkappa/CSL [RBP-J …
Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines.
Zhao B, Mar JC, Maruo S, Lee S, Gewurz BE, Johannsen E, Holton K, Rubio R, Takada K, Quackenbush J, Kieff E. Zhao B, et al. Among authors: kieff e. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):337-42. doi: 10.1073/pnas.1017419108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173222 Free PMC article.
312 results