Yang XW - Search Results

1

Network organization of the huntingtin proteomic interactome in mammalian brain.

Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Shirasaki DI, et al. Among authors: yang xw. Neuron. 2012 Jul 12;75(1):41-57. doi: 10.1016/j.neuron.2012.05.024. Neuron. 2012. PMID: 22794259 Free PMC article.

2

Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Gu X, et al. Among authors: yang xw. Neuron. 2005 May 5;46(3):433-44. doi: 10.1016/j.neuron.2005.03.025. Neuron. 2005. PMID: 15882643 Free article.

3

FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains.

Lobo MK, Karsten SL, Gray M, Geschwind DH, Yang XW. Lobo MK, et al. Among authors: yang xw. Nat Neurosci. 2006 Mar;9(3):443-52. doi: 10.1038/nn1654. Epub 2006 Feb 19. Nat Neurosci. 2006. PMID: 16491081

4

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.

Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Gray M, et al. Among authors: yang xw. J Neurosci. 2008 Jun 11;28(24):6182-95. doi: 10.1523/JNEUROSCI.0857-08.2008. J Neurosci. 2008. PMID: 18550760 Free PMC article.

5

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.

Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Gu X, et al. Among authors: yang xw. Neuron. 2009 Dec 24;64(6):828-40. doi: 10.1016/j.neuron.2009.11.020. Neuron. 2009. PMID: 20064390 Free PMC article.

6

Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.

Graham RK, Deng Y, Carroll J, Vaid K, Cowan C, Pouladi MA, Metzler M, Bissada N, Wang L, Faull RL, Gray M, Yang XW, Raymond LA, Hayden MR. Graham RK, et al. Among authors: yang xw. J Neurosci. 2010 Nov 10;30(45):15019-29. doi: 10.1523/JNEUROSCI.2071-10.2010. J Neurosci. 2010. PMID: 21068307 Free PMC article.

7

An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice.

Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. Wilburn B, et al. Among authors: yang xw. Neuron. 2011 May 12;70(3):427-40. doi: 10.1016/j.neuron.2011.03.021. Neuron. 2011. PMID: 21555070 Free PMC article.

8

Huntington's disease: flipping a switch on huntingtin.

Greiner ER, Yang XW. Greiner ER, et al. Among authors: yang xw. Nat Chem Biol. 2011 Jun 17;7(7):412-4. doi: 10.1038/nchembio.604. Nat Chem Biol. 2011. PMID: 21685885 No abstract available.

9

"Huntingtin holiday": progress toward an antisense therapy for Huntington's disease.

Lu XH, Yang XW. Lu XH, et al. Among authors: yang xw. Neuron. 2012 Jun 21;74(6):964-6. doi: 10.1016/j.neuron.2012.06.001. Neuron. 2012. PMID: 22726826 Free PMC article.

10

Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.

Lee CY, Cantle JP, Yang XW. Lee CY, et al. Among authors: yang xw. FEBS J. 2013 Sep;280(18):4382-94. doi: 10.1111/febs.12418. Epub 2013 Jul 31. FEBS J. 2013. PMID: 23829302 Free PMC article. Review.

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