Seon BK - Search Results

1

A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancer.

Rosen LS, Hurwitz HI, Wong MK, Goldman J, Mendelson DS, Figg WD, Spencer S, Adams BJ, Alvarez D, Seon BK, Theuer CP, Leigh BR, Gordon MS. Rosen LS, et al. Among authors: seon bk. Clin Cancer Res. 2012 Sep 1;18(17):4820-9. doi: 10.1158/1078-0432.CCR-12-0098. Epub 2012 Jul 5. Clin Cancer Res. 2012. PMID: 22767667 Free PMC article. Clinical Trial.

2

An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer.

Gordon MS, Robert F, Matei D, Mendelson DS, Goldman JW, Chiorean EG, Strother RM, Seon BK, Figg WD, Peer CJ, Alvarez D, Adams BJ, Theuer CP, Rosen LS. Gordon MS, et al. Among authors: seon bk. Clin Cancer Res. 2014 Dec 1;20(23):5918-26. doi: 10.1158/1078-0432.CCR-14-1143. Epub 2014 Sep 26. Clin Cancer Res. 2014. PMID: 25261556 Free PMC article. Clinical Trial.

3

A Phase II Clinical Trial of TRC105 (Anti-Endoglin Antibody) in Adults With Advanced/Metastatic Urothelial Carcinoma.

Apolo AB, Karzai FH, Trepel JB, Alarcon S, Lee S, Lee MJ, Tomita Y, Cao L, Yu Y, Merino MJ, Madan RA, Parnes HL, Steinberg SM, Rodriguez BW, Seon BK, Gulley JL, Arlen PM, Dawson NA, Figg WD, Dahut WL. Apolo AB, et al. Among authors: seon bk. Clin Genitourin Cancer. 2017 Feb;15(1):77-85. doi: 10.1016/j.clgc.2016.05.010. Epub 2016 May 27. Clin Genitourin Cancer. 2017. PMID: 27328856 Free PMC article. Clinical Trial.

4

An Open Label Phase Ib Dose Escalation Study of TRC105 (Anti-Endoglin Antibody) with Axitinib in Patients with Metastatic Renal Cell Carcinoma.

Choueiri TK, Michaelson MD, Posadas EM, Sonpavde GP, McDermott DF, Nixon AB, Liu Y, Yuan Z, Seon BK, Walsh M, Jivani MA, Adams BJ, Theuer CP. Choueiri TK, et al. Among authors: seon bk. Oncologist. 2019 Feb;24(2):202-210. doi: 10.1634/theoncologist.2018-0299. Epub 2018 Sep 6. Oncologist. 2019. PMID: 30190302 Free PMC article. Clinical Trial.

5

Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies.

Matsuno F, Haruta Y, Kondo M, Tsai H, Barcos M, Seon BK. Matsuno F, et al. Among authors: seon bk. Clin Cancer Res. 1999 Feb;5(2):371-82. Clin Cancer Res. 1999. PMID: 10037187

6

Association of serum endoglin with metastasis in patients with colorectal, breast, and other solid tumors, and suppressive effect of chemotherapy on the serum endoglin.

Takahashi N, Kawanishi-Tabata R, Haba A, Tabata M, Haruta Y, Tsai H, Seon BK. Takahashi N, et al. Among authors: seon bk. Clin Cancer Res. 2001 Mar;7(3):524-32. Clin Cancer Res. 2001. PMID: 11297243

7

Long-lasting complete inhibition of human solid tumors in SCID mice by targeting endothelial cells of tumor vasculature with antihuman endoglin immunotoxin.

Seon BK, Matsuno F, Haruta Y, Kondo M, Barcos M. Seon BK, et al. Clin Cancer Res. 1997 Jul;3(7):1031-44. Clin Cancer Res. 1997. PMID: 9815781

8

Antiangiogenic therapy of established tumors in human skin/severe combined immunodeficiency mouse chimeras by anti-endoglin (CD105) monoclonal antibodies, and synergy between anti-endoglin antibody and cyclophosphamide.

Takahashi N, Haba A, Matsuno F, Seon BK. Takahashi N, et al. Among authors: seon bk. Cancer Res. 2001 Nov 1;61(21):7846-54. Cancer Res. 2001. PMID: 11691802

9

Synergy between anti-endoglin (CD105) monoclonal antibodies and TGF-beta in suppression of growth of human endothelial cells.

She X, Matsuno F, Harada N, Tsai H, Seon BK. She X, et al. Among authors: seon bk. Int J Cancer. 2004 Jan 10;108(2):251-7. doi: 10.1002/ijc.11551. Int J Cancer. 2004. PMID: 14639611

10

Anti-endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculature.

Uneda S, Toi H, Tsujie T, Tsujie M, Harada N, Tsai H, Seon BK. Uneda S, et al. Among authors: seon bk. Int J Cancer. 2009 Sep 15;125(6):1446-53. doi: 10.1002/ijc.24482. Int J Cancer. 2009. PMID: 19533687 Free PMC article.

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