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Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice.
Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L. Han MH, et al. Among authors: axtell rc. J Exp Med. 2012 Jul 2;209(7):1325-34. doi: 10.1084/jem.20101974. Epub 2012 Jun 25. J Exp Med. 2012. PMID: 22734047 Free PMC article.
Inhibitory role for GABA in autoimmune inflammation.
Bhat R, Axtell R, Mitra A, Miranda M, Lock C, Tsien RW, Steinman L. Bhat R, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2580-5. doi: 10.1073/pnas.0915139107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133656 Free PMC article.
Angiotensin II sustains brain inflammation in mice via TGF-beta.
Lanz TV, Ding Z, Ho PP, Luo J, Agrawal AN, Srinagesh H, Axtell R, Zhang H, Platten M, Wyss-Coray T, Steinman L. Lanz TV, et al. J Clin Invest. 2010 Aug;120(8):2782-94. doi: 10.1172/JCI41709. Epub 2010 Jul 12. J Clin Invest. 2010. PMID: 20628203 Free PMC article.
Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.
Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L. Grant JL, et al. Among authors: axtell rc. Sci Transl Med. 2012 Aug 1;4(145):145ra105. doi: 10.1126/scitranslmed.3004145. Sci Transl Med. 2012. PMID: 22855462 Free PMC article.
Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation.
Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, Hla T, Han MH. Garris CS, et al. Among authors: axtell rc. Nat Immunol. 2013 Nov;14(11):1166-72. doi: 10.1038/ni.2730. Epub 2013 Sep 29. Nat Immunol. 2013. PMID: 24076635 Free PMC article.
Type 1 interferons cool the inflamed brain.
Axtell RC, Steinman L. Axtell RC, et al. Immunity. 2008 May;28(5):600-2. doi: 10.1016/j.immuni.2008.04.006. Immunity. 2008. PMID: 18482563 Free article.
135 results