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Immune self-reactivity triggered by drug-modified HLA-peptide repertoire.
Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J. Illing PT, et al. Nature. 2012 Jun 28;486(7404):554-8. doi: 10.1038/nature11147. Nature. 2012. PMID: 22722860
Human leukocyte antigen-associated drug hypersensitivity.
Illing PT, Vivian JP, Purcell AW, Rossjohn J, McCluskey J. Illing PT, et al. Curr Opin Immunol. 2013 Feb;25(1):81-9. doi: 10.1016/j.coi.2012.10.002. Epub 2012 Nov 8. Curr Opin Immunol. 2013. PMID: 23141566 Review.
The cellular redox environment alters antigen presentation.
Trujillo JA, Croft NP, Dudek NL, Channappanavar R, Theodossis A, Webb AI, Dunstone MA, Illing PT, Butler NS, Fett C, Tscharke DC, Rossjohn J, Perlman S, Purcell AW. Trujillo JA, et al. Among authors: illing pt. J Biol Chem. 2014 Oct 3;289(40):27979-91. doi: 10.1074/jbc.M114.573402. Epub 2014 Aug 18. J Biol Chem. 2014. PMID: 25135637 Free PMC article.
A comprehensive analysis of peptides presented by HLA-A1.
Giam K, Ayala-Perez R, Illing PT, Schittenhelm RB, Croft NP, Purcell AW, Dudek NL. Giam K, et al. Among authors: illing pt. Tissue Antigens. 2015 Jun;85(6):492-6. doi: 10.1111/tan.12565. Epub 2015 Apr 16. Tissue Antigens. 2015. PMID: 25880248
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP. Pymm P, et al. Among authors: illing pt. Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218747 Free PMC article.
49 results