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The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development.
Simpfendorfer KR, Olsson LM, Manjarrez Orduño N, Khalili H, Simeone AM, Katz MS, Lee AT, Diamond B, Gregersen PK. Simpfendorfer KR, et al. Among authors: simeone am. Hum Mol Genet. 2012 Sep 1;21(17):3918-25. doi: 10.1093/hmg/dds220. Epub 2012 Jun 7. Hum Mol Genet. 2012. PMID: 22678060 Free PMC article.
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