Klucken J - Search Results

1

Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway.

Klucken J, Poehler AM, Ebrahimi-Fakhari D, Schneider J, Nuber S, Rockenstein E, Schlötzer-Schrehardt U, Hyman BT, McLean PJ, Masliah E, Winkler J. Klucken J, et al. Autophagy. 2012 May 1;8(5):754-66. doi: 10.4161/auto.19371. Epub 2012 May 1. Autophagy. 2012. PMID: 22647715 Free PMC article.

2

Neuritic alterations and neural system dysfunction in Alzheimer's disease and dementia with Lewy bodies.

Klucken J, McLean PJ, Gomez-Tortosa E, Ingelsson M, Hyman BT. Klucken J, et al. Neurochem Res. 2003 Nov;28(11):1683-91. doi: 10.1023/a:1026061021946. Neurochem Res. 2003. PMID: 14584822 Review.

3

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity.

Klucken J, Shin Y, Masliah E, Hyman BT, McLean PJ. Klucken J, et al. J Biol Chem. 2004 Jun 11;279(24):25497-502. doi: 10.1074/jbc.M400255200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044495 Free article.

4

Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro.

McLean PJ, Klucken J, Shin Y, Hyman BT. McLean PJ, et al. Among authors: klucken j. Biochem Biophys Res Commun. 2004 Aug 27;321(3):665-9. doi: 10.1016/j.bbrc.2004.07.021. Biochem Biophys Res Commun. 2004. PMID: 15358157

5

A single amino acid substitution differentiates Hsp70-dependent effects on alpha-synuclein degradation and toxicity.

Klucken J, Shin Y, Hyman BT, McLean PJ. Klucken J, et al. Biochem Biophys Res Commun. 2004 Dec 3;325(1):367-73. doi: 10.1016/j.bbrc.2004.10.037. Biochem Biophys Res Commun. 2004. PMID: 15522241

6

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.

Shin Y, Klucken J, Patterson C, Hyman BT, McLean PJ. Shin Y, et al. Among authors: klucken j. J Biol Chem. 2005 Jun 24;280(25):23727-34. doi: 10.1074/jbc.M503326200. Epub 2005 Apr 21. J Biol Chem. 2005. PMID: 15845543 Free article.

7

Alpha-synuclein and chaperones in dementia with Lewy bodies.

Cantuti-Castelvetri I, Klucken J, Ingelsson M, Ramasamy K, McLean PJ, Frosch MP, Hyman BT, Standaert DG. Cantuti-Castelvetri I, et al. Among authors: klucken j. J Neuropathol Exp Neurol. 2005 Dec;64(12):1058-66. doi: 10.1097/01.jnen.0000190063.90440.69. J Neuropathol Exp Neurol. 2005. PMID: 16319716

8

Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies.

Klucken J, Ingelsson M, Shin Y, Irizarry MC, Hedley-Whyte ET, Frosch M, Growdon J, McLean P, Hyman BT. Klucken J, et al. Acta Neuropathol. 2006 Feb;111(2):101-8. doi: 10.1007/s00401-005-0027-7. Epub 2006 Feb 16. Acta Neuropathol. 2006. PMID: 16482476

9

Detection of novel intracellular alpha-synuclein oligomeric species by fluorescence lifetime imaging.

Klucken J, Outeiro TF, Nguyen P, McLean PJ, Hyman BT. Klucken J, et al. FASEB J. 2006 Oct;20(12):2050-7. doi: 10.1096/fj.05-5422com. FASEB J. 2006. PMID: 17012257

10

Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation.

Outeiro TF, Klucken J, Strathearn KE, Liu F, Nguyen P, Rochet JC, Hyman BT, McLean PJ. Outeiro TF, et al. Among authors: klucken j. Biochem Biophys Res Commun. 2006 Dec 22;351(3):631-8. doi: 10.1016/j.bbrc.2006.10.085. Epub 2006 Oct 26. Biochem Biophys Res Commun. 2006. PMID: 17081499 Free PMC article.

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