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723 results

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Peinado H, et al. Among authors: bromberg j. Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Nat Med. 2012. PMID: 22635005 Free PMC article.
Stat3 mediates expression of autotaxin in breast cancer.
Azare J, Doane A, Leslie K, Chang Q, Berishaj M, Nnoli J, Mark K, Al-Ahmadie H, Gerald W, Hassimi M, Viale A, Stracke M, Lyden D, Bromberg J. Azare J, et al. Among authors: bromberg j. PLoS One. 2011;6(11):e27851. doi: 10.1371/journal.pone.0027851. Epub 2011 Nov 28. PLoS One. 2011. PMID: 22140473 Free PMC article.
STAT3 negatively regulates thyroid tumorigenesis.
Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D, Bromberg JF. Couto JP, et al. Among authors: bromberg jf. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2361-70. doi: 10.1073/pnas.1201232109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891351 Free PMC article.
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.
Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L, Wels J, Theilen T, Granitto S, Zhang X, Cotari J, Alpaugh ML, de Stanchina E, Manova K, Li M, Bonafe M, Ceccarelli C, Taffurelli M, Santini D, Altan-Bonnet G, Kaplan R, Norton L, Nishimoto N, Huszar D, Lyden D, Bromberg J. Chang Q, et al. Among authors: bromberg j. Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706. Neoplasia. 2013. PMID: 23814496 Free PMC article.
Double-stranded DNA in exosomes: a novel biomarker in cancer detection.
Thakur BK, Zhang H, Becker A, Matei I, Huang Y, Costa-Silva B, Zheng Y, Hoshino A, Brazier H, Xiang J, Williams C, Rodriguez-Barrueco R, Silva JM, Zhang W, Hearn S, Elemento O, Paknejad N, Manova-Todorova K, Welte K, Bromberg J, Peinado H, Lyden D. Thakur BK, et al. Among authors: bromberg j. Cell Res. 2014 Jun;24(6):766-9. doi: 10.1038/cr.2014.44. Epub 2014 Apr 8. Cell Res. 2014. PMID: 24710597 Free PMC article. No abstract available.
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.
Papaspyridonos M, Matei I, Huang Y, do Rosario Andre M, Brazier-Mitouart H, Waite JC, Chan AS, Kalter J, Ramos I, Wu Q, Williams C, Wolchok JD, Chapman PB, Peinado H, Anandasabapathy N, Ocean AJ, Kaplan RN, Greenfield JP, Bromberg J, Skokos D, Lyden D. Papaspyridonos M, et al. Among authors: bromberg j. Nat Commun. 2015 Apr 29;6:6840. doi: 10.1038/ncomms7840. Nat Commun. 2015. PMID: 25924227 Free PMC article.
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH, Grandgenett PM, Hollingsworth MA, Jain M, Mallya K, Batra SK, Jarnagin WR, Schwartz RE, Matei I, Peinado H, Stanger BZ, Bromberg J, Lyden D. Costa-Silva B, et al. Among authors: bromberg j. Nat Cell Biol. 2015 Jun;17(6):816-26. doi: 10.1038/ncb3169. Epub 2015 May 18. Nat Cell Biol. 2015. PMID: 25985394 Free PMC article.
Tumour exosome integrins determine organotropic metastasis.
Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K, Wexler LH, Narendran A, Schwartz GK, Healey JH, Sandstrom P, Labori KJ, Kure EH, Grandgenett PM, Hollingsworth MA, de Sousa M, Kaur S, Jain M, Mallya K, Batra SK, Jarnagin WR, Brady MS, Fodstad O, Muller V, Pantel K, Minn AJ, Bissell MJ, Garcia BA, Kang Y, Rajasekhar VK, Ghajar CM, Matei I, Peinado H, Bromberg J, Lyden D. Hoshino A, et al. Among authors: bromberg j. Nature. 2015 Nov 19;527(7578):329-35. doi: 10.1038/nature15756. Epub 2015 Oct 28. Nature. 2015. PMID: 26524530 Free PMC article.
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
Sansone P, Ceccarelli C, Berishaj M, Chang Q, Rajasekhar VK, Perna F, Bowman RL, Vidone M, Daly L, Nnoli J, Santini D, Taffurelli M, Shih NN, Feldman M, Mao JJ, Colameco C, Chen J, DeMichele A, Fabbri N, Healey JH, Cricca M, Gasparre G, Lyden D, Bonafé M, Bromberg J. Sansone P, et al. Among authors: bromberg j. Nat Commun. 2016 Feb 9;7:10442. doi: 10.1038/ncomms10442. Nat Commun. 2016. PMID: 26858125 Free PMC article.
723 results