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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases.
Brown DS, Cumming JG, Bethel P, Finlayson J, Gerhardt S, Nash I, Pauptit RA, Pike KG, Reid A, Snelson W, Swallow S, Thompson C. Brown DS, et al. Among authors: thompson c. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3879-83. doi: 10.1016/j.bmcl.2012.04.116. Epub 2012 May 2. Bioorg Med Chem Lett. 2012. PMID: 22608965
Herbicidal aryldiones incorporating a 5-methoxy-[1,2,5]triazepane ring.
Smejkal T, Hachisu S, Scutt JN, Willetts NJ, Sayer D, Wildsmith L, Oliver S, Thompson C, Muehlebach M. Smejkal T, et al. Among authors: thompson c. Bioorg Med Chem Lett. 2018 Feb 1;28(3):339-343. doi: 10.1016/j.bmcl.2017.12.042. Epub 2017 Dec 20. Bioorg Med Chem Lett. 2018. PMID: 29317169
Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activity.
Brown DG, Bernstein PR, Wu Y, Urbanek RA, Becker CW, Throner SR, Dembofsky BT, Steelman GB, Lazor LA, Scott CW, Wood MW, Wesolowski SS, Nugiel DA, Koch S, Yu J, Pivonka DE, Li S, Thompson C, Zacco A, Elmore CS, Schroeder P, Liu J, Hurley CA, Ward S, Hunt HJ, Williams K, McLaughlin J, Hoesch V, Sydserff S, Maier D, Aharony D. Brown DG, et al. Among authors: thompson c. ACS Med Chem Lett. 2012 Nov 12;4(1):46-51. doi: 10.1021/ml300262e. eCollection 2013 Jan 10. ACS Med Chem Lett. 2012. PMID: 24900562 Free PMC article.
Pharmacokinetics of Tarlatamab, a Delta-Like Ligand-3 (DLL3) Targeted Half-Life Extended Bispecific T-Cell Engager (BiTE®) Immunotherapy in Adult Patients with Previously Treated Small-Cell Lung Cancer: Results from DeLLphi-300, a Phase I Multiple-Dose-Escalation Study.
Minocha M, Thompson CG, Murphy A, Zhou Y, Brandl C, Parkes A, Chen X, Yu B, Martinez P, Houk BE. Minocha M, et al. Among authors: thompson cg. Clin Pharmacokinet. 2024 Nov 26. doi: 10.1007/s40262-024-01451-7. Online ahead of print. Clin Pharmacokinet. 2024. PMID: 39589690
Development and evaluation of an antigen targeting lateral flow test for Crimean-Congo Haemorrhagic Fever.
Thompson CR, Bozkurt I, Cosgun Y, Blundell P, Duvoix A, Johnson M, Hedef H, Arslan FG, Umudum BA, Bilek HC, Tanyel E, Pektaş AN, Taşseten TN, Bakir M, Büyüktuna SA, Olçar Y, Yilmaz FA, Arslan M, Al-Hilfi RA, Hasan HA, Khaleel RI, Aufi IM, Mahdi SG, Aakef IR, Shakir HA, Hussein AA, Abdulhadi NA, Mohsin ZA, Korukluoglu G, Cubas Atienzar AI, Fletcher TE, Adams E. Thompson CR, et al. EBioMedicine. 2024 Nov 20;110:105460. doi: 10.1016/j.ebiom.2024.105460. Online ahead of print. EBioMedicine. 2024. PMID: 39571306 Free article.
Measuring hospital inpatient Procedure Access Inequality in the United States.
Bergman A, David G, Nathan A, Giri J, Ryan M, Chikermane S, Thompson C, Clancy S, Gunnarsson C. Bergman A, et al. Among authors: thompson c. Health Aff Sch. 2024 Nov 6;2(11):qxae142. doi: 10.1093/haschl/qxae142. eCollection 2024 Nov. Health Aff Sch. 2024. PMID: 39564567 Free PMC article.
Health impacts of takeaway management zones around schools in six different local authorities across England: a public health modelling study using PRIMEtime.
Rogers NT, Amies-Cull B, Adams J, Chang M, Cummins S, Derbyshire D, Hassan S, Keeble M, Liu B, Medina-Lara A, Savory B, Rahilly J, Smith R, Thompson C, White M, Mytton O, Burgoine T. Rogers NT, et al. Among authors: thompson c. BMC Med. 2024 Nov 19;22(1):545. doi: 10.1186/s12916-024-03739-8. BMC Med. 2024. PMID: 39563350 Free PMC article.
7,796 results