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Extent, causes, and consequences of small RNA expression variation in human adipose tissue.
Parts L, Hedman ÅK, Keildson S, Knights AJ, Abreu-Goodger C, van de Bunt M, Guerra-Assunção JA, Bartonicek N, van Dongen S, Mägi R, Nisbet J, Barrett A, Rantalainen M, Nica AC, Quail MA, Small KS, Glass D, Enright AJ, Winn J; MuTHER Consortium; Deloukas P, Dermitzakis ET, McCarthy MI, Spector TD, Durbin R, Lindgren CM. Parts L, et al. Among authors: rantalainen m. PLoS Genet. 2012;8(5):e1002704. doi: 10.1371/journal.pgen.1002704. Epub 2012 May 10. PLoS Genet. 2012. PMID: 22589741 Free PMC article.
The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue.
Drong AW, Nicholson G, Hedman AK, Meduri E, Grundberg E, Small KS, Shin SY, Bell JT, Karpe F, Soranzo N, Spector TD, McCarthy MI, Deloukas P, Rantalainen M, Lindgren CM; MolPAGE Consortia. Drong AW, et al. Among authors: rantalainen m. PLoS One. 2013;8(2):e55923. doi: 10.1371/journal.pone.0055923. Epub 2013 Feb 19. PLoS One. 2013. PMID: 23431366 Free PMC article.
MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.
Rantalainen M, Herrera BM, Nicholson G, Bowden R, Wills QF, Min JL, Neville MJ, Barrett A, Allen M, Rayner NW, Fleckner J, McCarthy MI, Zondervan KT, Karpe F, Holmes CC, Lindgren CM. Rantalainen M, et al. PLoS One. 2011;6(11):e27338. doi: 10.1371/journal.pone.0027338. Epub 2011 Nov 15. PLoS One. 2011. PMID: 22102887 Free PMC article.
Robust Linear Models for Cis-eQTL Analysis.
Rantalainen M, Lindgren CM, Holmes CC. Rantalainen M, et al. PLoS One. 2015 May 18;10(5):e0127882. doi: 10.1371/journal.pone.0127882. eCollection 2015. PLoS One. 2015. PMID: 25992607 Free PMC article.
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.
Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U; MolPAGE Consortium; Donnelly P, Illig T, Adamski J, Suhre K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D, Holmes E, McCarthy MI, Holmes CC. Nicholson G, et al. Among authors: rantalainen m. PLoS Genet. 2011 Sep;7(9):e1002270. doi: 10.1371/journal.pgen.1002270. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931564 Free PMC article.
Human metabolic profiles are stably controlled by genetic and environmental variation.
Nicholson G, Rantalainen M, Maher AD, Li JV, Malmodin D, Ahmadi KR, Faber JH, Hallgrímsdóttir IB, Barrett A, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U, The Molpage Consortium, Silverman BW, Donnelly P, Nicholson JK, Allen M, Zondervan KT, Lindon JC, Spector TD, McCarthy MI, Holmes E, Baunsgaard D, Holmes CC. Nicholson G, et al. Among authors: rantalainen m. Mol Syst Biol. 2011 Aug 30;7:525. doi: 10.1038/msb.2011.57. Mol Syst Biol. 2011. PMID: 21878913 Free PMC article.
Beta-Poisson model for single-cell RNA-seq data analyses.
Vu TN, Wills QF, Kalari KR, Niu N, Wang L, Rantalainen M, Pawitan Y. Vu TN, et al. Among authors: rantalainen m. Bioinformatics. 2016 Jul 15;32(14):2128-35. doi: 10.1093/bioinformatics/btw202. Epub 2016 Apr 19. Bioinformatics. 2016. PMID: 27153638
66 results