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Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.
Scherman MS, North EJ, Jones V, Hess TN, Grzegorzewicz AE, Kasagami T, Kim IH, Merzlikin O, Lenaerts AJ, Lee RE, Jackson M, Morisseau C, McNeil MR. Scherman MS, et al. Among authors: hess tn. Bioorg Med Chem. 2012 May 15;20(10):3255-62. doi: 10.1016/j.bmc.2012.03.058. Epub 2012 Mar 31. Bioorg Med Chem. 2012. PMID: 22522007 Free PMC article.
Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37.
Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Honda JR, et al. Am J Respir Cell Mol Biol. 2020 Mar;62(3):354-363. doi: 10.1165/rcmb.2018-0278OC. Am J Respir Cell Mol Biol. 2020. PMID: 31545652 Free PMC article.