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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulch… See abstract for full author list ➔ Estrada K, et al. Among authors: brown ma. Nat Genet. 2012 Apr 15;44(5):491-501. doi: 10.1038/ng.2249. Nat Genet. 2012. PMID: 22504420 Free PMC article.
Suggestive linkage of the parathyroid receptor type 1 to osteoporosis.
Duncan EL, Brown MA, Sinsheimer J, Bell J, Carr AJ, Wordsworth BP, Wass JA. Duncan EL, et al. Among authors: brown ma. J Bone Miner Res. 1999 Dec;14(12):1993-9. doi: 10.1359/jbmr.1999.14.12.1993. J Bone Miner Res. 1999. PMID: 10620056 Free article.
Genetic studies of osteoporosis.
Brown MA, Duncan EL. Brown MA, et al. Expert Rev Mol Med. 1999 Oct 19;1999:1-18. doi: 10.1017/S1462399499000964. Expert Rev Mol Med. 1999. PMID: 14585121
Influence of LRP5 polymorphisms on normal variation in BMD.
Koay MA, Woon PY, Zhang Y, Miles LJ, Duncan EL, Ralston SH, Compston JE, Cooper C, Keen R, Langdahl BL, MacLelland A, O'Riordan J, Pols HA, Reid DM, Uitterlinden AG, Wass JA, Brown MA. Koay MA, et al. Among authors: brown ma. J Bone Miner Res. 2004 Oct;19(10):1619-27. doi: 10.1359/JBMR.040704. Epub 2004 Jul 7. J Bone Miner Res. 2004. PMID: 15355556 Free article.
PTHR1 polymorphisms influence BMD variation through effects on the growing skeleton.
Vilariño-Güell C, Miles LJ, Duncan EL, Ralston SH, Compston JE, Cooper C, Langdahl BL, Maclelland A, Pols HA, Reid DM, Uitterlinden AG, Steer CD, Tobias JH, Wass JA, Brown MA. Vilariño-Güell C, et al. Among authors: brown ma. Calcif Tissue Int. 2007 Oct;81(4):270-8. doi: 10.1007/s00223-007-9072-7. Epub 2007 Sep 21. Calcif Tissue Int. 2007. PMID: 17885720
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Barton A, et al. Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794857 Free PMC article.
Genetic studies in osteoporosis--the end of the beginning.
Duncan EL, Brown MA. Duncan EL, et al. Among authors: brown ma. Arthritis Res Ther. 2008;10(5):214. doi: 10.1186/ar2479. Epub 2008 Sep 12. Arthritis Res Ther. 2008. PMID: 18828878 Free PMC article. Review.
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims AM, Whittaker P, Kumanduri V, Zhai G, Glaser B, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Spector TD, Brown MA, Peltonen L, Smith GD, Deloukas P, Evans DM. Timpson NJ, et al. Among authors: brown ma. Hum Mol Genet. 2009 Apr 15;18(8):1510-7. doi: 10.1093/hmg/ddp052. Epub 2009 Jan 30. Hum Mol Genet. 2009. PMID: 19181680 Free PMC article.
1,561 results