Wolf A - Search Results

1

Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.

Deraeve C, Guo Z, Bon RS, Blankenfeldt W, DiLucrezia R, Wolf A, Menninger S, Stigter EA, Wetzel S, Choidas A, Alexandrov K, Waldmann H, Goody RS, Wu YW. Deraeve C, et al. Among authors: wolf a. J Am Chem Soc. 2012 May 2;134(17):7384-91. doi: 10.1021/ja211305j. Epub 2012 Apr 22. J Am Chem Soc. 2012. PMID: 22480322

2

The cholesterol membrane anchor of the Hedgehog protein confers stable membrane association to lipid-modified proteins.

Peters C, Wolf A, Wagner M, Kuhlmann J, Waldmann H. Peters C, et al. Among authors: wolf a. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8531-6. doi: 10.1073/pnas.0308449101. Epub 2004 May 26. Proc Natl Acad Sci U S A. 2004. PMID: 15163793 Free PMC article.

3

The Ras pathway modulator melophlin A targets dynamins.

Knoth T, Warburg K, Katzka C, Rai A, Wolf A, Brockmeyer A, Janning P, Reubold TF, Eschenburg S, Manstein DJ, Hübel K, Kaiser M, Waldmann H. Knoth T, et al. Among authors: wolf a. Angew Chem Int Ed Engl. 2009;48(39):7240-5. doi: 10.1002/anie.200902023. Angew Chem Int Ed Engl. 2009. PMID: 19722243 No abstract available.

4

High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38alpha.

Simard JR, Grütter C, Pawar V, Aust B, Wolf A, Rabiller M, Wulfert S, Robubi A, Klüter S, Ottmann C, Rauh D. Simard JR, et al. Among authors: wolf a. J Am Chem Soc. 2009 Dec 30;131(51):18478-88. doi: 10.1021/ja907795q. J Am Chem Soc. 2009. PMID: 19950957

5

Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions.

Rose R, Erdmann S, Bovens S, Wolf A, Rose M, Hennig S, Waldmann H, Ottmann C. Rose R, et al. Among authors: wolf a. Angew Chem Int Ed Engl. 2010 Jun 1;49(24):4129-32. doi: 10.1002/anie.200907203. Angew Chem Int Ed Engl. 2010. PMID: 20437433 No abstract available.

6

Structure-guided development of selective RabGGTase inhibitors.

Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H. Bon RS, et al. Among authors: wolf a. Angew Chem Int Ed Engl. 2011 May 16;50(21):4957-61. doi: 10.1002/anie.201101210. Epub 2011 Apr 21. Angew Chem Int Ed Engl. 2011. PMID: 21520375 No abstract available.

7

Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.

Samatov TR, Wolf A, Odenwälder P, Bessonov S, Deraeve C, Bon RS, Waldmann H, Lührmann R. Samatov TR, et al. Among authors: wolf a. Chembiochem. 2012 Mar 19;13(5):640-4. doi: 10.1002/cbic.201100790. Epub 2012 Feb 14. Chembiochem. 2012. PMID: 22334518 No abstract available.

8

Development of selective, potent RabGGTase inhibitors.

Stigter EA, Guo Z, Bon RS, Wu YW, Choidas A, Wolf A, Menninger S, Waldmann H, Blankenfeldt W, Goody RS. Stigter EA, et al. Among authors: wolf a. J Med Chem. 2012 Oct 11;55(19):8330-40. doi: 10.1021/jm300624s. Epub 2012 Oct 3. J Med Chem. 2012. PMID: 22963166

9

A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling.

Brüggenthies JB, Fiore A, Russier M, Bitsina C, Brötzmann J, Kordes S, Menninger S, Wolf A, Conti E, Eickhoff JE, Murray PJ. Brüggenthies JB, et al. Among authors: wolf a. J Biol Chem. 2022 Dec;298(12):102629. doi: 10.1016/j.jbc.2022.102629. Epub 2022 Oct 20. J Biol Chem. 2022. PMID: 36273589 Free PMC article.

10

IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.

Andlovic B, Heilmann G, Ninck S, Andrei SA, Centorrino F, Higuchi Y, Kato N, Brunsveld L, Arkin M, Menninger S, Choidas A, Wolf A, Klebl B, Kaschani F, Kaiser M, Eickhoff J, Ottmann C. Andlovic B, et al. Among authors: wolf a. Cell Chem Biol. 2023 Jun 15;30(6):573-590.e6. doi: 10.1016/j.chembiol.2023.04.005. Epub 2023 May 1. Cell Chem Biol. 2023. PMID: 37130519 Free article.

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