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Page 1
Structure-guided development of selective RabGGTase inhibitors.
Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H. Bon RS, et al. Among authors: choidas a. Angew Chem Int Ed Engl. 2011 May 16;50(21):4957-61. doi: 10.1002/anie.201101210. Epub 2011 Apr 21. Angew Chem Int Ed Engl. 2011. PMID: 21520375 No abstract available.
Development of selective, potent RabGGTase inhibitors.
Stigter EA, Guo Z, Bon RS, Wu YW, Choidas A, Wolf A, Menninger S, Waldmann H, Blankenfeldt W, Goody RS. Stigter EA, et al. Among authors: choidas a. J Med Chem. 2012 Oct 11;55(19):8330-40. doi: 10.1021/jm300624s. Epub 2012 Oct 3. J Med Chem. 2012. PMID: 22963166
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, Jamieson AM, Langdon WY, Ikeda F, Fededa JP, Cronin SJ, Nitsch R, Schultz-Fademrecht C, Eickhoff J, Menninger S, Unger A, Torka R, Gruber T, Hinterleitner R, Baier G, Wolf D, Ullrich A, Klebl BM, Penninger JM. Paolino M, et al. Among authors: choidas a. Nature. 2014 Mar 27;507(7493):508-12. doi: 10.1038/nature12998. Epub 2014 Feb 19. Nature. 2014. PMID: 24553136 Free PMC article.
Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction.
Kremer L, Schultz-Fademrecht C, Baumann M, Habenberger P, Choidas A, Klebl B, Kordes S, Schöler HR, Sterneckert J, Ziegler S, Schneider G, Waldmann H. Kremer L, et al. Among authors: choidas a. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13021-13025. doi: 10.1002/anie.201707394. Epub 2017 Sep 18. Angew Chem Int Ed Engl. 2017. PMID: 28833911
Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.
Höing S, Yeh TY, Baumann M, Martinez NE, Habenberger P, Kremer L, Drexler HCA, Küchler P, Reinhardt P, Choidas A, Zischinsky ML, Zischinsky G, Nandini S, Ledray AP, Ketcham SA, Reinhardt L, Abo-Rady M, Glatza M, King SJ, Nussbaumer P, Ziegler S, Klebl B, Schroer TA, Schöler HR, Waldmann H, Sterneckert J. Höing S, et al. Among authors: choidas a. Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6. doi: 10.1016/j.chembiol.2017.12.014. Epub 2018 Jan 27. Cell Chem Biol. 2018. PMID: 29396292 Free PMC article.
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A. Sollberger G, et al. Among authors: choidas a. Sci Immunol. 2018 Aug 24;3(26):eaar6689. doi: 10.1126/sciimmunol.aar6689. Sci Immunol. 2018. PMID: 30143555
Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth.
Reckzeh ES, Karageorgis G, Schwalfenberg M, Ceballos J, Nowacki J, Stroet MCM, Binici A, Knauer L, Brand S, Choidas A, Strohmann C, Ziegler S, Waldmann H. Reckzeh ES, et al. Among authors: choidas a. Cell Chem Biol. 2019 Sep 19;26(9):1214-1228.e25. doi: 10.1016/j.chembiol.2019.06.005. Epub 2019 Jul 11. Cell Chem Biol. 2019. PMID: 31303578 Free article.
Small-molecule inhibitors of human mitochondrial DNA transcription.
Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG. Bonekamp NA, et al. Among authors: choidas a. Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16. Nature. 2020. PMID: 33328633
29 results