Guo RT - Search Results

1

Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars.

Chan HC, Zhu Y, Hu Y, Ko TP, Huang CH, Ren F, Chen CC, Ma Y, Guo RT, Sun Y. Chan HC, et al. Among authors: guo rt. Protein Cell. 2012 Feb;3(2):123-31. doi: 10.1007/s13238-012-2026-5. Epub 2012 Mar 17. Protein Cell. 2012. PMID: 22426981 Free PMC article.

2

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo RT, Kuo CJ, Chou CC, Ko TP, Shr HL, Liang PH, Wang AH. Guo RT, et al. J Biol Chem. 2004 Feb 6;279(6):4903-12. doi: 10.1074/jbc.M310161200. Epub 2003 Nov 15. J Biol Chem. 2004. PMID: 14617622 Free article.

3

A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products.

Guo RT, Kuo CJ, Ko TP, Chou CC, Liang PH, Wang AH. Guo RT, et al. Biochemistry. 2004 Jun 22;43(24):7678-86. doi: 10.1021/bi036336d. Biochemistry. 2004. PMID: 15196010

4

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo RT, Ko TP, Chen AP, Kuo CJ, Wang AH, Liang PH. Guo RT, et al. J Biol Chem. 2005 May 27;280(21):20762-74. doi: 10.1074/jbc.M502121200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788389 Free article.

5

Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures.

Sun HY, Ko TP, Kuo CJ, Guo RT, Chou CC, Liang PH, Wang AH. Sun HY, et al. Among authors: guo rt. J Bacteriol. 2005 Dec;187(23):8137-48. doi: 10.1128/JB.187.23.8137-8148.2005. J Bacteriol. 2005. PMID: 16291686 Free PMC article.

6

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Chang TH, Guo RT, Ko TP, Wang AH, Liang PH. Chang TH, et al. Among authors: guo rt. J Biol Chem. 2006 May 26;281(21):14991-5000. doi: 10.1074/jbc.M512886200. Epub 2006 Mar 22. J Biol Chem. 2006. PMID: 16554305 Free article.

7

Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.

Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH. Guo RT, et al. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. doi: 10.1073/pnas.0702254104. Epub 2007 May 29. Proc Natl Acad Sci U S A. 2007. PMID: 17535895 Free PMC article.

8

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis.

Jeng WY, Ko TP, Liu CI, Guo RT, Liu CL, Shr HL, Wang AH. Jeng WY, et al. Among authors: guo rt. Nucleic Acids Res. 2008 Mar;36(5):1567-77. doi: 10.1093/nar/gkm1176. Epub 2008 Jan 21. Nucleic Acids Res. 2008. PMID: 18208836 Free PMC article.

9

Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases.

Kuo CJ, Guo RT, Lu IL, Liu HG, Wu SY, Ko TP, Wang AH, Liang PH. Kuo CJ, et al. Among authors: guo rt. J Biomed Biotechnol. 2008;2008:841312. doi: 10.1155/2008/841312. J Biomed Biotechnol. 2008. PMID: 18382620 Free PMC article.

10

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.

K-M Chen C, Hudock MP, Zhang Y, Guo RT, Cao R, No JH, Liang PH, Ko TP, Chang TH, Chang SC, Song Y, Axelson J, Kumar A, Wang AH, Oldfield E. K-M Chen C, et al. Among authors: guo rt. J Med Chem. 2008 Sep 25;51(18):5594-607. doi: 10.1021/jm800325y. J Med Chem. 2008. PMID: 18800762 Free PMC article.

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