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Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions.
Bochkov VN, Philippova M, Oskolkova O, Kadl A, Furnkranz A, Karabeg E, Afonyushkin T, Gruber F, Breuss J, Minchenko A, Mechtcheriakova D, Hohensinner P, Rychli K, Wojta J, Resink T, Erne P, Binder BR, Leitinger N. Bochkov VN, et al. Circ Res. 2006 Oct 13;99(8):900-8. doi: 10.1161/01.RES.0000245485.04489.ee. Epub 2006 Sep 14. Circ Res. 2006. PMID: 16973904
Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo.
Jyrkkänen HK, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen AL. Jyrkkänen HK, et al. Circ Res. 2008 Jul 3;103(1):e1-9. doi: 10.1161/CIRCRESAHA.108.176883. Epub 2008 Jun 5. Circ Res. 2008. PMID: 18535259
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