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Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle.
Franko A, von Kleist-Retzow JC, Böse M, Sanchez-Lasheras C, Brodesser S, Krut O, Kunz WS, Wiedermann D, Hoehn M, Stöhr O, Moll L, Freude S, Krone W, Schubert M, Wiesner RJ. Franko A, et al. J Mol Med (Berl). 2012 Oct;90(10):1145-60. doi: 10.1007/s00109-012-0887-y. Epub 2012 Mar 13. J Mol Med (Berl). 2012. PMID: 22411022
Liver adapts mitochondrial function to insulin resistant and diabetic states in mice.
Franko A, von Kleist-Retzow JC, Neschen S, Wu M, Schommers P, Böse M, Kunze A, Hartmann U, Sanchez-Lasheras C, Stoehr O, Huntgeburth M, Brodesser S, Irmler M, Beckers J, de Angelis MH, Paulsson M, Schubert M, Wiesner RJ. Franko A, et al. J Hepatol. 2014 Apr;60(4):816-23. doi: 10.1016/j.jhep.2013.11.020. Epub 2013 Nov 28. J Hepatol. 2014. PMID: 24291365
Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I.
Sobek S, Dalla Rosa I, Pommier Y, Bornholz B, Kalfalah F, Zhang H, Wiesner RJ, von Kleist-Retzow JC, Hillebrand F, Schaal H, Mielke C, Christensen MO, Boege F. Sobek S, et al. Nucleic Acids Res. 2013 Nov;41(21):9848-57. doi: 10.1093/nar/gkt768. Epub 2013 Aug 27. Nucleic Acids Res. 2013. PMID: 23982517 Free PMC article.
Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice.
Franko A, Irmler M, Prehn C, Heinzmann SS, Schmitt-Kopplin P, Adamski J, Beckers J, von Kleist-Retzow JC, Wiesner R, Häring HU, Heni M, Birkenfeld AL, de Angelis MH. Franko A, et al. Among authors: von kleist retzow jc. Biomedicines. 2022 Mar 6;10(3):616. doi: 10.3390/biomedicines10030616. Biomedicines. 2022. PMID: 35327418 Free PMC article.
A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations.
Möllers M, Maniura-Weber K, Kiseljakovic E, Bust M, Hayrapetyan A, Jaksch M, Helm M, Wiesner RJ, von Kleist-Retzow JC. Möllers M, et al. Nucleic Acids Res. 2005 Sep 30;33(17):5647-58. doi: 10.1093/nar/gki876. Print 2005. Nucleic Acids Res. 2005. PMID: 16199753 Free PMC article.
47 results