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Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase.
Cuesta-Domínguez Á, Ortega M, Ormazábal C, Santos-Roncero M, Galán-Díez M, Steegmann JL, Figuera Á, Arranz E, Vizmanos JL, Bueren JA, Río P, Fernández-Ruiz E. Cuesta-Domínguez Á, et al. PLoS One. 2012;7(2):e32451. doi: 10.1371/journal.pone.0032451. Epub 2012 Feb 27. PLoS One. 2012. PMID: 22384256 Free PMC article.
Candida albicans beta-glucan exposure is controlled by the fungal CEK1-mediated mitogen-activated protein kinase pathway that modulates immune responses triggered through dectin-1.
Galán-Díez M, Arana DM, Serrano-Gómez D, Kremer L, Casasnovas JM, Ortega M, Cuesta-Domínguez A, Corbí AL, Pla J, Fernández-Ruiz E. Galán-Díez M, et al. Infect Immun. 2010 Apr;78(4):1426-36. doi: 10.1128/IAI.00989-09. Epub 2010 Jan 25. Infect Immun. 2010. PMID: 20100861 Free PMC article.
T cells kill bacteria captured by transinfection from dendritic cells and confer protection in mice.
Cruz-Adalia A, Ramirez-Santiago G, Calabia-Linares C, Torres-Torresano M, Feo L, Galán-Díez M, Fernández-Ruiz E, Pereiro E, Guttmann P, Chiappi M, Schneider G, Carrascosa JL, Chichón FJ, Martínez Del Hoyo G, Sánchez-Madrid F, Veiga E. Cruz-Adalia A, et al. Cell Host Microbe. 2014 May 14;15(5):611-22. doi: 10.1016/j.chom.2014.04.006. Cell Host Microbe. 2014. PMID: 24832455 Free article.
BCR-JAK2 drives a myeloproliferative neoplasm in transplanted mice.
Cuesta-Domínguez Á, León-Rico D, Álvarez L, Díez B, Bodega-Mayor I, Baños R, Martín-Rey MÁ, Santos-Roncero M, Gaspar ML, Martín-Acosta P, Almarza E, Bueren JA, Río P, Fernández-Ruiz E. Cuesta-Domínguez Á, et al. J Pathol. 2015 Jun;236(2):219-28. doi: 10.1002/path.4513. Epub 2015 Mar 3. J Pathol. 2015. PMID: 25664618
TYK2 Variants in B-Acute Lymphoblastic Leukaemia.
Turrubiartes-Martínez E, Bodega-Mayor I, Delgado-Wicke P, Molina-Jiménez F, Casique-Aguirre D, González-Andrade M, Rapado I, Camós M, Díaz-de-Heredia C, Barragán E, Ramírez-Orellana M, Aguado B, Figuera Á, Martínez-López J, Fernández-Ruiz E. Turrubiartes-Martínez E, et al. Genes (Basel). 2020 Nov 28;11(12):1434. doi: 10.3390/genes11121434. Genes (Basel). 2020. PMID: 33260630 Free PMC article. Clinical Trial.
74 results