Kordes S - Search Results

1

A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer.

Kordes S, Richel DJ, Klümpen HJ, Weterman MJ, Stevens AJ, Wilmink JW. Kordes S, et al. Invest New Drugs. 2013 Feb;31(1):85-91. doi: 10.1007/s10637-012-9802-1. Epub 2012 Feb 25. Invest New Drugs. 2013. PMID: 22367239 Free PMC article. Clinical Trial.

2

Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer.

Kordes S, Klümpen HJ, Weterman MJ, Schellens JH, Richel DJ, Wilmink JW. Kordes S, et al. Cancer Chemother Pharmacol. 2015 Jun;75(6):1135-41. doi: 10.1007/s00280-015-2730-y. Epub 2015 Mar 31. Cancer Chemother Pharmacol. 2015. PMID: 25822310 Free PMC article. Clinical Trial.

3

Preoperative chemoradiation therapy in combination with panitumumab for patients with resectable esophageal cancer: the PACT study.

Kordes S, van Berge Henegouwen MI, Hulshof MC, Bergman JJ, van der Vliet HJ, Kapiteijn E, van Laarhoven HW, Richel DJ, Klinkenbijl JH, Meijer SL, Wilmink JW. Kordes S, et al. Int J Radiat Oncol Biol Phys. 2014 Sep 1;90(1):190-6. doi: 10.1016/j.ijrobp.2014.05.022. Int J Radiat Oncol Biol Phys. 2014. PMID: 25195993 Clinical Trial.

4

Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial.

Kordes S, Pollak MN, Zwinderman AH, Mathôt RA, Weterman MJ, Beeker A, Punt CJ, Richel DJ, Wilmink JW. Kordes S, et al. Lancet Oncol. 2015 Jul;16(7):839-47. doi: 10.1016/S1470-2045(15)00027-3. Epub 2015 Jun 8. Lancet Oncol. 2015. PMID: 26067687 Clinical Trial.

5

Targeted therapy for advanced esophagogastric adenocarcinoma.

Kordes S, Cats A, Meijer SL, van Laarhoven HW. Kordes S, et al. Crit Rev Oncol Hematol. 2014 Apr;90(1):68-76. doi: 10.1016/j.critrevonc.2013.10.004. Epub 2013 Oct 12. Crit Rev Oncol Hematol. 2014. PMID: 24183912 Review.

6

Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases.

Dunbar KL, Perlatti B, Liu N, Cornelius A, Mummau D, Chiang YM, Hon L, Nimavat M, Pallas J, Kordes S, Ng HL, Harvey CJB. Dunbar KL, et al. Among authors: kordes s. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2310522120. doi: 10.1073/pnas.2310522120. Epub 2023 Nov 20. Proc Natl Acad Sci U S A. 2023. PMID: 37983497 Free PMC article.

7

Physics-based approach to extend a de novo TIM barrel with rationally designed helix-loop-helix motifs.

Kordes S, Beck J, Shanmugaratnam S, Flecks M, Höcker B. Kordes S, et al. Protein Eng Des Sel. 2023 Jan 21;36:gzad012. doi: 10.1093/protein/gzad012. Protein Eng Des Sel. 2023. PMID: 37707513

8

A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling.

Brüggenthies JB, Fiore A, Russier M, Bitsina C, Brötzmann J, Kordes S, Menninger S, Wolf A, Conti E, Eickhoff JE, Murray PJ. Brüggenthies JB, et al. Among authors: kordes s. J Biol Chem. 2022 Dec;298(12):102629. doi: 10.1016/j.jbc.2022.102629. Epub 2022 Oct 20. J Biol Chem. 2022. PMID: 36273589 Free PMC article.

9

A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels.

Kordes S, Romero-Romero S, Lutz L, Höcker B. Kordes S, et al. Protein Sci. 2022 Feb;31(2):513-527. doi: 10.1002/pro.4249. Epub 2021 Dec 16. Protein Sci. 2022. PMID: 34865275 Free PMC article.

10

The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.

Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. Among authors: kordes s. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.

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