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Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation.
Kärkkäinen AM, Kotimaa A, Huusko J, Kholova I, Heinonen SE, Stefanska A, Dijkstra MH, Purhonen H, Hämäläinen E, Mäkinen PI, Turunen MP, Ylä-Herttuala S. Kärkkäinen AM, et al. Among authors: heinonen se. Blood. 2009 Apr 30;113(18):4468-75. doi: 10.1182/blood-2008-07-171108. Epub 2008 Dec 10. Blood. 2009. PMID: 19074006 Free article.
Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects.
Jauhiainen S, Häkkinen SK, Toivanen PI, Heinonen SE, Jyrkkänen HK, Kansanen E, Leinonen H, Levonen AL, Ylä-Herttuala S. Jauhiainen S, et al. Among authors: heinonen se. Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1617-24. doi: 10.1161/ATVBAHA.111.225961. Epub 2011 Apr 7. Arterioscler Thromb Vasc Biol. 2011. PMID: 21474827
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