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Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
Ding J, Ning B, Gong W, Wen W, Wu K, Liang J, He G, Huang S, Sun W, Han T, Huang L, Cao G, Wu M, Xie W, Wang H. Ding J, et al. Among authors: han t. J Biol Chem. 2009 Nov 27;284(48):33311-9. doi: 10.1074/jbc.M109.046417. Epub 2009 Sep 29. J Biol Chem. 2009. PMID: 19801633 Free PMC article.
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.
Bard-Chapeau EA, Li S, Ding J, Zhang SS, Zhu HH, Princen F, Fang DD, Han T, Bailly-Maitre B, Poli V, Varki NM, Wang H, Feng GS. Bard-Chapeau EA, et al. Among authors: han t. Cancer Cell. 2011 May 17;19(5):629-39. doi: 10.1016/j.ccr.2011.03.023. Cancer Cell. 2011. PMID: 21575863 Free PMC article.
5,243 results