Stock TC - Search Results

1

Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial.

Fleishaker DL, Garcia Meijide JA, Petrov A, Kohen MD, Wang X, Menon S, Stock TC, Mebus CA, Goodrich JM, Mayer HB, Zeiher BG. Fleishaker DL, et al. Among authors: stock tc. Arthritis Res Ther. 2012 Jan 17;14(1):R11. doi: 10.1186/ar3685. Arthritis Res Ther. 2012. PMID: 22251436 Free PMC article. Clinical Trial.

2

Improved disease activity with fosdagrocorat (PF-04171327), a partial agonist of the glucocorticoid receptor, in patients with rheumatoid arthritis: a Phase 2 randomized study.

Stock T, Fleishaker D, Wang X, Mukherjee A, Mebus C. Stock T, et al. Int J Rheum Dis. 2017 Aug;20(8):960-970. doi: 10.1111/1756-185X.13053. Epub 2017 Mar 22. Int J Rheum Dis. 2017. PMID: 28328159 Free PMC article. Clinical Trial.

3

Efficacy and safety of CE-224,535, an antagonist of P2X7 receptor, in treatment of patients with rheumatoid arthritis inadequately controlled by methotrexate.

Stock TC, Bloom BJ, Wei N, Ishaq S, Park W, Wang X, Gupta P, Mebus CA. Stock TC, et al. J Rheumatol. 2012 Apr;39(4):720-7. doi: 10.3899/jrheum.110874. Epub 2012 Mar 1. J Rheumatol. 2012. PMID: 22382341 Clinical Trial.

4

In Vitro and In Vivo Investigation of Potential for Complex CYP3A Interaction for PF-00251802 (Dagrocorat), a Novel Dissociated Agonist of the Glucocorticoid Receptor.

Ripp SL, Mukherjee A, Eng H, Stock T, Fleishaker D, Checchio T, Tammara B. Ripp SL, et al. Clin Pharmacol Drug Dev. 2018 Mar;7(3):244-255. doi: 10.1002/cpdd.411. Epub 2017 Nov 7. Clin Pharmacol Drug Dev. 2018. PMID: 29112329 Free PMC article. Clinical Trial.

5

Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study.

Ruperto N, Brunner HI, Zuber Z, Tzaribachev N, Kingsbury DJ, Foeldvari I, Horneff G, Smolewska E, Vehe RK, Hazra A, Wang R, Mebus CA, Alvey C, Lamba M, Krishnaswami S, Stock TC, Wang M, Suehiro R, Martini A, Lovell DJ; Pediatric Rheumatology International Trials Organization (PRINTO); Pediatric Rheumatology Collaborative Study Group (PRCSG). Ruperto N, et al. Among authors: stock tc. Pediatr Rheumatol Online J. 2017 Dec 28;15(1):86. doi: 10.1186/s12969-017-0212-y. Pediatr Rheumatol Online J. 2017. PMID: 29282090 Free PMC article. Clinical Trial.

6

Modified- versus immediate-release tofacitinib in Japanese rheumatoid arthritis patients: a randomized, phase III, non-inferiority study.

Tanaka Y, Sugiyama N, Toyoizumi S, Lukic T, Lamba M, Zhang R, Chen C, Stock T, Valdez H, Mojcik C, Fan H, Deng C, Yuasa H. Tanaka Y, et al. Rheumatology (Oxford). 2019 Jan 1;58(1):70-79. doi: 10.1093/rheumatology/key250. Rheumatology (Oxford). 2019. PMID: 30137547 Free PMC article. Clinical Trial.

7

Model-Informed Development and Registration of a Once-Daily Regimen of Extended-Release Tofacitinib.

Lamba M, Hutmacher MM, Furst DE, Dikranian A, Dowty ME, Conrado D, Stock T, Nduaka C, Cook J, Krishnaswami S. Lamba M, et al. Clin Pharmacol Ther. 2017 Jun;101(6):745-753. doi: 10.1002/cpt.576. Epub 2017 Feb 9. Clin Pharmacol Ther. 2017. PMID: 27859030 Free PMC article.

8

Extended-Release Once-Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate-Release Tofacitinib and Impact of Food.

Lamba M, Wang R, Fletcher T, Alvey C, Kushner J 4th, Stock TC. Lamba M, et al. Among authors: stock tc. J Clin Pharmacol. 2016 Nov;56(11):1362-1371. doi: 10.1002/jcph.734. J Clin Pharmacol. 2016. PMID: 26970526 Free PMC article. Clinical Trial.

9

Development and validation of a Level A in-vitro in-vivo correlation for tofacitinib modified-release tablets using extrudable core system osmotic delivery technology.

Kushner J 4th, Lamba M, Stock T, Wang R, Nemeth MA, Alvey C, Chen R, DeMatteo V, Blanchard A. Kushner J 4th, et al. Eur J Pharm Sci. 2020 Apr 30;147:105200. doi: 10.1016/j.ejps.2019.105200. Epub 2019 Dec 19. Eur J Pharm Sci. 2020. PMID: 31863865 Free article. Clinical Trial.

10

Model-based drug development: a rational approach to efficiently accelerate drug development.

Milligan PA, Brown MJ, Marchant B, Martin SW, van der Graaf PH, Benson N, Nucci G, Nichols DJ, Boyd RA, Mandema JW, Krishnaswami S, Zwillich S, Gruben D, Anziano RJ, Stock TC, Lalonde RL. Milligan PA, et al. Among authors: stock tc. Clin Pharmacol Ther. 2013 Jun;93(6):502-14. doi: 10.1038/clpt.2013.54. Epub 2013 Mar 14. Clin Pharmacol Ther. 2013. PMID: 23588322

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