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Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.
Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Suchiman HE, Jacobsen R, McGue M, Stevnsner T, Bohr VA, de Craen AJ, Westendorp RG, Schreiber S, Slagboom PE, Nebel A, Vaupel JW, Christensen K, Christiansen L. Soerensen M, et al. Among authors: beekman m. Age (Dordr). 2013 Apr;35(2):487-500. doi: 10.1007/s11357-011-9373-7. Epub 2012 Jan 12. Age (Dordr). 2013. PMID: 22234866 Free PMC article.
Heritabilities of apolipoprotein and lipid levels in three countries.
Beekman M, Heijmans BT, Martin NG, Pedersen NL, Whitfield JB, DeFaire U, van Baal GC, Snieder H, Vogler GP, Slagboom PE, Boomsma DI. Beekman M, et al. Twin Res. 2002 Apr;5(2):87-97. doi: 10.1375/1369052022956. Twin Res. 2002. PMID: 11931686 Free article.
Combined association and linkage analysis applied to the APOE locus.
Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HE, Snieder H, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Slagboom PE, Boomsma DI. Beekman M, et al. Genet Epidemiol. 2004 May;26(4):328-37. doi: 10.1002/gepi.10318. Genet Epidemiol. 2004. PMID: 15095392 Free article.
Variation in the human TP53 gene affects old age survival and cancer mortality.
van Heemst D, Mooijaart SP, Beekman M, Schreuder J, de Craen AJ, Brandt BW, Slagboom PE, Westendorp RG; Long Life study group. van Heemst D, et al. Among authors: beekman m. Exp Gerontol. 2005 Jan-Feb;40(1-2):11-5. doi: 10.1016/j.exger.2004.10.001. Exp Gerontol. 2005. PMID: 15732191 Review.
Reduced insulin/IGF-1 signalling and human longevity.
van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG. van Heemst D, et al. Among authors: beekman m. Aging Cell. 2005 Apr;4(2):79-85. doi: 10.1111/j.1474-9728.2005.00148.x. Aging Cell. 2005. PMID: 15771611 Free article.
398 results